dl-tetramisolehydrochloride
Tetramisole hydrochloride
CAS: 5086-74-8
Molecular Formula: C11H13ClN2S
dl-tetramisolehydrochloride - Names and Identifiers
| Name | Tetramisole hydrochloride |
| Synonyms | citarin bayer9051 anthelvet (+-)-anthelvet Tetramisole HCl DL-Tetramisole HCl Tetramisole hydrochloride dl-tetramisolehydrochloride DL-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride dl-6-phenyl-2,3,5,6-tetrahydroimidazole(2,1-b)thiazole-hydrochloride (+-)-2,3,5,6-tetrahydro-6-phenylimidazo(2,1-b)thiazolemonohydrochloride 1-b)thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,(+-)-imidazo( |
| CAS | 5086-74-8 |
| EINECS | 225-799-5 |
| InChI | InChI=1/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H |
| InChIKey | LAZPBGZRMVRFKY-UHFFFAOYSA-N |
dl-tetramisolehydrochloride - Physico-chemical Properties
| Molecular Formula | C11H13ClN2S |
| Molar Mass | 240.75 |
| Melting Point | 266-267°C(lit.) |
| Water Solubility | 200 g/L (20 ºC) |
| Solubility | Methanol (Slightly), Water (Slightly, Heated) |
| Appearance | Solid |
| Color | White to Off-White |
| Merck | 13,5480 |
| BRN | 4358989 |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Stability | Hygroscopic |
| Physical and Chemical Properties | Tetraimidazole hydrochloride also known as DL-2,3,5, 6-tetrahydro-6-phenylimidazo [2,1-b] thiazole hydrochloride, white crystalline powder, bitter and astringent, soluble in water, methanol, slightly soluble in ethanol, insoluble in acetone, is a broad-spectrum veterinary anthelmintics with high efficiency and low toxicity. |
| Use | Used as levamisole intermediates, anti-worm drugs |
| In vitro study | Tetramisole is orally nontoxic and is administered at a potent low dose by injection against all adult and juvenile gastrointestinal and pulmonary nematodes tested in 14 different hosts. Tetramisole (10 μg/mL) acts on the worm virus, causing a sustained contraction of the isolated muscle. Tetramisole acts on the muscle of the roundworm, reducing its resting potential from 34 mV to 10 mV, and causing a direct or indirect stimulation of the muscle before acting on the cat with a high K Tetramisole (0.1 mM), enhances the twitch response of the muscles. Tetramisole (0.1 mM) acts on chickens to enhance the preparation of the twitch response and reverse the inhibitory effect of Tubocurarine, producing reversible neuromuscular blockade and muscle contracture. |
| In vivo study | Tetramisole (2 mg/kg, I. v.) acting on cats, after a delay of 20 seconds, a strong contraction of the nictitating membrane is produced, accompanied by a brief drop in blood pressure followed by a sustained rise that lasts for up to 20 minutes. Tetramisole (2 mg/kg) produced a greater contractile response than did cats not treated with reserpine. Tetramisole (5-10 mg/kg, I. v.) in rabbits caused a transient sharp drop in blood pressure, partly antagonized by atropine. Tetramisole (15 mg/kg) treated for 3 weeks, the number of eggs of the fecal worm began to increase and continued to rise to 12 weeks. |
dl-tetramisolehydrochloride - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| RTECS | NJ5950000 |
| HS Code | 29349990 |
| Toxicity | LD50 in mice, rats (mg/kg): 22, 24 i.v.; 84, 130 s.c.; 210, 480 orally (Thienpoint) |
dl-tetramisolehydrochloride - Reference Information
| use | tetraimidazole hydrochloride is a biological response regulator with insect repellent activity. Insecticidal drugs (nematodes); immunomodulatory preparations. used as levamisole intermediate and anti-worm drug |
| biological activity | Tetramisole is a mixture of right-handed and left-handed isomers, used as insect repellent. |
Last Update：2024-04-09 02:00:09
Supplier List
Spot supply
Product Name: Tetramisole Hydrochloride Visit Supplier Webpage Request for quotationCAS: 5086-74-8
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: Tetramisole hydrochloride Request for quotation
CAS: 5086-74-8
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Wechat: +86 19849939632
CAS: 5086-74-8
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Wechat: +86 19849939632
Product Name: Tetramisole hydrochloride Request for quotation
CAS: 5086-74-8
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 5086-74-8
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Spot supply
Product Name: Tetramisole Hydrochloride Visit Supplier Webpage Request for quotationCAS: 5086-74-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: Tetramisole hydrochloride Request for quotation
CAS: 5086-74-8
Tel:
Email: bella@whkmbk.com
Mobile: 16631161866
CAS: 5086-74-8
Tel:
Email: bella@whkmbk.com
Mobile: 16631161866
Spot supply
Product Name: Tetramisole Hydrochloride Visit Supplier Webpage Request for quotationCAS: 5086-74-8
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: Tetramisole hydrochloride Request for quotation
CAS: 5086-74-8
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Wechat: +86 19849939632
CAS: 5086-74-8
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Wechat: +86 19849939632
Product Name: Tetramisole hydrochloride Request for quotation
CAS: 5086-74-8
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 5086-74-8
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Spot supply
Product Name: Tetramisole Hydrochloride Visit Supplier Webpage Request for quotationCAS: 5086-74-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: Tetramisole hydrochloride Request for quotation
CAS: 5086-74-8
Tel:
Email: bella@whkmbk.com
Mobile: 16631161866
CAS: 5086-74-8
Tel:
Email: bella@whkmbk.com
Mobile: 16631161866
View History