Molecular Formula | C20H34O2 |
Molar Mass | 306.48 |
Density | 1.09±0.1 g/cm3(Predicted) |
Melting Point | 193-194 °C |
Boling Point | 422.3±18.0 °C(Predicted) |
Solubility | DMSO: 10 mM |
Appearance | Powder |
pKa | 14.48±0.60(Predicted) |
Storage Condition | 2-8℃ |
In vitro study | Kauran-16,17-diol (ent-Kauran-16β,17-diol) down-regulates Bcl-2 by disruption of the Ap-2α/Rb transcription activating complex and induces E2F1 up-regulation in MCF-7 cells. |
biological activity | Kauran-16,17-diol (ent-Kauran-16β,17-diol) is a natural diterpenoid compound, has anti-tumor induced apoptosis activity. It inhibited LPS-induced NO production in RAW 264.7 cells with an IC50 value of 17 μm. |