ethyl2-(2-benzyloxycarbonylaMinothiazol-4-yl)acetate

ethyl2-(2-benzyloxycarbonylaMinothiazol-4-yl)acetate - Names and Identifiers

Name	ethyl2-(2-benzyloxycarbonylaMinothiazol-4-yl)acetate
Synonyms	EBTA Ebta ethyl2-(2-benzyloxycarbonylaMinothiazol-4-yl)acetate benzyl 4-((ethoxycarbonyl)methyl)thiazol-2-ylcarbamate EBTAEthyl 2-(2-benzyloxycarbonylaminothiazol-4-yl) acetate ethyl 2-[2-(phenylmethoxycarbonylamino)-1,3-thiazol-4-yl]acetate 2-[2-(phenylmethoxycarbonylamino)-4-thiazolyl]acetic acid ethyl ester 4-Thiazoleacetic acid, 2-[[(phenylmethoxy)carbonyl]amino]-, ethyl ester
CAS	92592-02-4

ethyl2-(2-benzyloxycarbonylaMinothiazol-4-yl)acetate - Physico-chemical Properties

Molecular Formula	C15H16N2O4S
Molar Mass	320.36
Density	1.326±0.06 g/cm3(Predicted)
pKa	4.87±0.70(Predicted)
Storage Condition	2-8°C

ethyl2-(2-benzyloxycarbonylaMinothiazol-4-yl)acetate - Introduction

acetate is an organic compound whose chemical formula is C14H15NO4S. The following is an introduction to some of its properties, uses, formulation and safety information:

Nature:
1. Appearance: ethyl2-(acetate) is a colorless to light yellow liquid.
2. Solubility: It is soluble in organic solvents, such as methanol and ethanol, but insoluble in water.
3. Melting point and boiling point: Its melting point and boiling point are about 30-40°C and about 180°C, respectively.

Use:
ethyl2-acetate has many applications in organic synthesis:
1. It can be used as a pharmaceutical intermediate for the synthesis of biologically active compounds.
2. It can also be used as a chiral reagent for the synthesis of chiral compounds.
3. It can be used as a synthetic raw material for pesticides and fungicides in the agricultural field.

Method:
The method of preparing ethyl2-(-) acetate is as follows:
1. First, under alkaline conditions, 2-benzyl amino ketone is generated by reaction with ammonia and benzoyl chloride.
2. Next, 2-benzylaminoketone is reacted with thiazolaldehyde to obtain 2-benzylaminothiazolone.
3. finally, 2-benzylaminothiazolone reacts with ethyl acetate to generate ethyl2-(Br) acetate under acid catalysis.

Safety Information:
1. ethy12-() acetate should avoid contact with fire and high temperature during storage and use to prevent fire or explosion.
2. It may be irritating to the eyes and skin, so direct contact should be avoided during operation.
3. Use should wear personal protective equipment, such as gloves and goggles.
4. in the use of organic synthesis compounds, should follow good laboratory safety procedures.

Last Update：2024-04-09 21:01:54