febrinina
Allobarbital
CAS: 58-15-1
Molecular Formula: C13H17N3O
febrinina - Names and Identifiers
febrinina - Physico-chemical Properties
| Molecular Formula | C13H17N3O |
| Molar Mass | 231.29 |
| Density | 1.0744 (rough estimate) |
| Melting Point | 107-109°C(lit.) |
| Boling Point | 373.38°C (rough estimate) |
| Flash Point | 125.9°C |
| Water Solubility | 5.55 g/100 mL |
| Vapor Presure | 0.000333mmHg at 25°C |
| Appearance | Crystalline Powder, Crystals and/or Chunks |
| Color | Off-white to brownish |
| Merck | 14,474 |
| pKa | pKa 5.0 (Uncertain) |
| Storage Condition | Refrigerator |
| Stability | Stable. Incompatible with strong oxidizing agents, strong acids, strong bases. Light sensitive. Degrades under the action of mild oxidizing agents in the presence of moisture or water. |
| Sensitive | Air & Light Sensitive |
| Refractive Index | 1.6140 (estimate) |
| Physical and Chemical Properties | White leaf-like crystal or crystalline powder. No odor, slightly bitter. Stable in the air, but in the sun will deteriorate, when there is water, easy to react with weak oxidant. Soluble in alcohol, chloroform, benzene and ether, soluble in water. The solubility in water increases with the addition of sodium benzoate. The aqueous solution is weakly alkaline to litmus. The melting point was 107-109 °c. |
| Use | Antipyretic analgesic for Fever, Head Pain, Arthralgia, neuralgia, dysmenorrhea and active rheumatism |
febrinina - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R21/22 - Harmful in contact with skin and if swallowed. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | CD2625000 |
| TSCA | Yes |
| HS Code | 29331190 |
| Hazard Class | 6.1 |
| Packing Group | III |
| Toxicity | LD50 orally in rats: 1.7 g/kg (Hart) |
febrinina - Upstream Downstream Industry
febrinina - Nature
Open Data Verified Data
White leaf-like crystal or crystalline powder. No odor, slightly bitter. The melting point was 107-109 °c. lg the product is soluble in 1.5 ml ethanol, 12ml benzene, 1ml chloroform, 13ml ether, 18ml water. The solubility in water increases with the addition of sodium benzoate. The aqueous solution is weakly alkaline to litmus. Stable in the air, but in the sun will deteriorate, when there is water, easy to react with weak oxidant.
Last Update：2024-01-02 23:10:35
febrinina - Preparation Method
Open Data Verified Data
crude aminopyrine was obtained by catalytic hydrogenation of aminoantipyrine. Aminopyrine crude, ethanol, activated carbon to a certain temperature, stirring decolorization, pressure filtration, cooling crystallization, washing, drying can be.
Last Update：2022-01-01 09:27:07
febrinina - Use
Open Data Verified Data
crude aminopyrine was obtained by catalytic hydrogenation of aminoantipyrine. Aminopyrine crude, ethanol, activated carbon to a certain temperature, stirring decolorization, pressure filtration, cooling crystallization, washing, drying can be. Aminopyrine can be used as an analytical reagent for the determination of antimony, bismuth, bromine, cadmium, chlorine, cobalt, ketone, cyanide, gold, iron iodate, lead, nickel, nitric acid, nitrite, osmium, oxides of nitrogen, palladium, platinum, silver and zinc. Or antipyretic analgesic, for Fever, Head Pain, Arthralgia, neuralgia, dysmenorrhea and active rheumatism. Aminopyrine belongs to pyrazolone non-steroidal anti-inflammatory drugs, which has strong antipyretic, analgesic, anti-inflammatory and anti-rheumatic effects. But easy to cause agranulocytosis, aplastic anemia and so on. Clinical application has been decreasing.
Last Update：2022-01-01 09:27:08
febrinina - Use
Open Data Verified Data
rat oral LD50:1.7g/kg.
Last Update：2022-01-01 09:27:08
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CAS: 58-15-1
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CAS: 58-15-1
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Raw Materials for febrinina