fluorenylmethoxycarbonyl-l-3,4-difluorophenylalanine

fluorenylmethoxycarbonyl-l-3,4-difluorophenylalanine - Names and Identifiers

Name	FMOC-L-3,4-Difluorophe
Synonyms	FMOC-PHE(M,P-F2)-OH FMOC-PHE(3,4-F2)-OH fmoc-phe(m,p-f2)-oh Fmoc-phe(3,4-f2)-oh fmoc-phe(3,4-dif)-oh FMOC-PHE(3,4-DIF)-OH FMOC-L-PHE(3,4-F2)-OH fmoc-l-phe(3,4-f2)-oh FMOC-L-3,4-DIFLUOROPHE FMOC-L-3,4-Difluorophe fmoc-3,4-difluoro-l-phe-oh FMOC-3,4-DIFLUORO-L-PHE-OH fmoc-l-3,4-difluorophenylalanine FMOC-3,4-DIFLUORO-L-PHENYLALANINE fmoc-3,4-difluoro-l-phenylalanine fluorenylmethoxycarbonyl-l-3,4-difluorophenylalanine Fluorenylmethoxycarbonyl-L-3,4-difluorophenylalanine
CAS	198560-43-9

fluorenylmethoxycarbonyl-l-3,4-difluorophenylalanine - Physico-chemical Properties

Molecular Formula	C24H19F2NO4
Molar Mass	423.41
Density	1.357±0.06 g/cm3(Predicted)
Boling Point	622.7±55.0 °C(Predicted)
BRN	8947230
pKa	3.68±0.10(Predicted)
Storage Condition	Sealed in dry,2-8°C
Physical and Chemical Properties	Storage Conditions: 2-8 ℃ WGK Germany:3

fluorenylmethoxycarbonyl-l-3,4-difluorophenylalanine - Risk and Safety

Hazard Symbols	Xi - Irritant
WGK Germany	3
Hazard Note	Irritant

fluorenylmethoxycarbonyl-l-3,4-difluorophenylalanine - Introduction

FMOC-L-3,4-Difluorophe is an organic compound with the following properties:

1. Appearance: white crystalline powder.
2. Molecular formula: C17H15F2NO4.
3. Molecular weight: 345.30g/mol.
4. Melting Point: about 207-212 ° C.
5. Solubility: soluble in common organic solvents, such as dichloromethane, dimethyl sulfoxide and ethyl acetate.

FMOC-L-3,4-Difluorophe is mainly used in the field of organic synthesis, especially in the synthesis of peptides, and is often used as a building block for helical peptides and other polypeptides. It serves as a protecting group to temporarily protect natural amino acid residues from reaction with other chemical reagents during peptide synthesis. Upon completion of the synthesis, the protecting groups can be removed and reduced to the native amino acid residue.

The method of preparing FMOC-L-3,4-Difluorophe is generally obtained by an organic synthesis reaction. The specific steps include reacting alanine with an appropriate amount of 2,3, 5-trifluorobenzoic acid to obtain FMOC-L-3,4-Difluorophe. In this process, care needs to be taken to use appropriate auxiliaries and conditions to facilitate the reaction.

When using FMOC-L-3,4-Difluorophe, you need to pay attention to the following safety information:
1. Avoid inhalation of dust or contact with skin and eyes, should wear protective equipment.
2. During operation, it should be carried out in a well-ventilated laboratory environment.
3. In case of inhalation, ingestion or skin contact, wash the affected area immediately and seek medical help if necessary.
4. Keep the container sealed and store in a low temperature, dry and ventilated place.

Last Update：2024-04-10 22:29:15