fmoc-b-Homoasparagine(trt)

fmoc-b-Homoasparagine(trt) - Names and Identifiers

Name	Fmoc-L-beta-homoasparagine(Trt)
Synonyms	Fmoc-β-HoAsn(Trt)-OH FMOC-BETA-GLN(TRT)-OH FMoc-beta-HAsn(Trt)-OH FMOC-BETA-HOASN(TRT)-OH FMOC-ASN(TRT)-(C*CH2)OH fmoc-b-Homoasparagine(trt) Fmoc-L-beta-Homo-Asn(Trt)-OH FMOC-L-BETA-HOMOASPARAGINE(TRT) Fmoc-L-beta-homoasparagine(Trt) FMOC-GAMMA-TRITYL-L-BETA-HOMOASPARAGINE (3S)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-5-oxo-5-(tritylamino)pentanoic acid (3S)-3-(9H-Fluoren-9-Ylmethoxycarbonylamino)-5-Oxo-5-[Tri(Phenyl)Methylamino]Pentanoic Acid (3S)-3-(9H-Fluoren-9-ylmethoxycarbonylamino)-5-oxo-5-[tri(phenyl)methylamino]pentanoic acid
CAS	283160-20-3
EINECS	689-323-1
InChI	InChI=1/C39H34N2O5/c42-36(41-39(27-14-4-1-5-15-27,28-16-6-2-7-17-28)29-18-8-3-9-19-29)24-30(25-37(43)44)40-38(45)46-26-35-33-22-12-10-20-31(33)32-21-11-13-23-34(32)35/h1-23,30,35H,24-26H2,(H,40,45)(H,41,42)(H,43,44)/t30-/m0/s1

fmoc-b-Homoasparagine(trt) - Physico-chemical Properties

Molecular Formula	C39H34N2O5
Molar Mass	610.7
Density	1.256
Boling Point	873.4°C at 760 mmHg
Flash Point	482°C
Vapor Presure	1.3E-32mmHg at 25°C
Storage Condition	Sealed in dry,2-8°C
Refractive Index	1.636
MDL	MFCD03427579

fmoc-b-Homoasparagine(trt) - Risk and Safety

WGK Germany	3
FLUKA BRAND F CODES	10
Hazard Class	IRRITANT

fmoc-b-Homoasparagine(trt) - Introduction

Fmoc-L-beta-homoasparagine(Trt) (Fmoc-L-beta-homoasparagine(Trt)) is an organic compound with the chemical formula C38H32N2O5 and a relative molecular mass of 600.67g/mol.

The compound is mainly used for peptide synthesis in solid phase synthesis. It is an aromatic β-amino acid with good chemical stability and solubility, and can be used to establish a specific structure of the peptide chain. The valeric acid moiety provides the function of protecting the amino acid from destruction by unwanted reactions during synthesis. The fluorenylmethoxycarbonyl (Fmoc) group can be easily deprotected to further extend the synthetic peptide chain.

Fmoc-L-beta-homoasparagine(Trt) is usually prepared by synthesizing a series of intermediates to obtain the final product. In the specific preparation, the valeric acid portion of the β-amino acid is first synthesized and reacted to produce fluorenylmethoxycarbonylated valeric acid. It is then reacted with trityl amine in the presence of the corresponding reagent to form trityl amine hydrochloride. Finally, the fluorenomethoxy peptide moiety is combined with tritylamine hydrochloride to give Fmoc-L-beta-homoasparagine(Trt).

Regarding safety information, the use of Fmoc-L-beta-homoasparagine(Trt) requires attention to its toxicity and irritation. Appropriate personal protective equipment, such as lab gloves and goggles, should be worn during operation. At the same time, the operation should be carried out in a well-ventilated laboratory environment, avoiding contact with skin, eyes and inhalation. If you come into contact with this substance, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-10 22:29:15