fmoc-l-3-(4-pyridyl)-alanine - Names and Identifiers
fmoc-l-3-(4-pyridyl)-alanine - Physico-chemical Properties
Molecular Formula | C23H20N2O4
|
Molar Mass | 388.42 |
Density | 1.309±0.06 g/cm3(Predicted) |
Melting Point | 219 °C(dec.) |
Boling Point | 646.9±55.0 °C(Predicted) |
Flash Point | 345°C |
Solubility | Soluble in 0.1g in 4mL DMF(clearly soluble). |
Vapor Presure | 1.28E-17mmHg at 25°C |
Appearance | powder to crystal |
Color | White to Light yellow |
BRN | 7316905 |
pKa | 3.32±0.10(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.637 |
MDL | MFCD00672566 |
fmoc-l-3-(4-pyridyl)-alanine - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Safety Description | 24/25 - Avoid contact with skin and eyes.
|
WGK Germany | 3 |
HS Code | 29333990 |
Hazard Class | IRRITANT |
fmoc-l-3-(4-pyridyl)-alanine - Introduction
fmoc-3-(4-pyridyl)-L-alanine is an organic compound with the following properties:
1. Appearance: White or almost white crystalline powder.
2. Molecular formula: C22H20N2O4.
3. Molecular weight: 376.41g/mol.
4. Solubility: Soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF).
fmoc-3-(4-pyridyl)-L-alanine are mainly used in the field of peptide synthesis and solid phase synthesis. It is often used as a protecting group for amino acids, which can protect the α-amino and side chain functional groups of amino acids to avoid unnecessary side reactions in the synthesis reaction, thereby achieving selective synthesis. In addition, it can be used to synthesize peptides, proteins and other bioactive molecules.
Its preparation method is mainly obtained by chemical synthesis method, generally by alanine acylation reaction, the Fmoc protecting group is introduced into the 3 position, the 1-configuration of propyl amino acid is then introduced on the 4-pyridyl group.
Regarding the safety information of fmoc-3-(4-pyridyl)-L-alanine, the following matters need to be noted:
1. Wear appropriate personal protective equipment, such as lab gloves and safety glasses.
2. Avoid inhaling the vapor of the powder or solution, and operate in a well-ventilated place.
3. Avoid contact with skin and eyes, such as contact should be washed with water immediately.
4. Storage should be sealed, away from the fire and oxidant.
5. If necessary, please follow the relevant safety procedures and laboratory practices. In case of any discomfort or doubt, seek medical help immediately.
Last Update:2024-04-10 22:29:15