fmoc-l-4-aminophenylalanine

fmoc-l-4-aminophenylalanine - Names and Identifiers

Name	Fmoc-p-amino-Phe-OH
Synonyms	Fmoc-Phe(4-NH2)-OH FMOC-PHE(4-NH2)-OH Fmoc-p-amino-Phe-OH Fmoc-4-Amino-Phe-OH FMOC-L-PHE(4-NH2)-OH FMOC-P-AMINO-L-PHE-OH fmoc-l-4-aminophenylalanine Fmoc-4-Amino-L-phenylalanine FMoc-L-4-aMino-Phenylpropionic acid (S)-N-(9-Fluorenylmethyloxycarbonyl)-4-aminophenylalanine N-ALPHA-(9-FLUOROENYLMETHYLOXYCARBONYL)-4-AMINO-L-PHENYLALANINE (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(4-aminophenyl)propanoic acid
CAS	95753-56-3
EINECS	1806241-263-5
InChI	InChI=1/C24H22N2O4/c25-16-11-9-15(10-12-16)13-22(23(27)28)26-24(29)30-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14,25H2,(H,26,29)(H,27,28)/t22-/m0/s1

fmoc-l-4-aminophenylalanine - Physico-chemical Properties

Molecular Formula	C24H22N2O4
Molar Mass	402.44
Density	1.316±0.06 g/cm3(Predicted)
Boling Point	671.5±55.0 °C(Predicted)
pKa	3.63±0.10(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,2-8°C

fmoc-l-4-aminophenylalanine - Risk and Safety

Hazard Class

IRRITANT

fmoc-l-4-aminophenylalanine - Introduction

Fmoc-p-amino-Phe-OH(Fmoc-p-amino-Phe-OH) is an organic compound commonly used in peptide synthesis and solid phase synthesis.

Properties of the compound:
1. molecular formula: C23H19NO4
2. molecular weight: 373.41g/mol
3. Appearance: white or white solid
4. melting point: 220-223 ℃

Main uses of Fmoc-p-amino-Phe-OH:
1. Peptide synthesis: Amino acid residues are introduced in the synthesis of peptides and proteins.
2. solid phase synthesis: can be used as amino acid protection group in solid phase synthesis.
3. Drug research: In drug research and development, it is often used to synthesize biologically active peptide compounds.

The preparation method is generally as follows:
p-Amino-L-phenylalanine is reacted with Fmoc-Cl to form Fmoc-p-amino-Phe-OH. The reaction is carried out in a basic medium. Common solvents are dimethylformamide (DMF) and sodium aminohydride (NaNH2).

About safety information:
1. Fmoc-p-amino-Phe-OH there is no obvious toxicity under ideal conditions, it is still necessary to take appropriate laboratory safety measures and operating practices.
2. Wear appropriate personal protective equipment (e. g., lab gloves, glasses, and lab coat) during operation.
3. Avoid contact with skin and inhalation of dust during operation and avoid ingestion.
4. During storage and handling, keep the compounds separated from flammable substances, strong oxidants, etc.
5. In the event of an accident, flush the affected area immediately with plenty of water and seek medical assistance.

Last Update：2024-04-09 20:00:08