Name | hexafluorobenzene |
Synonyms | CP28 CP 28 Perfluorobenzene hexafluorobenzene benzene,hexafluoro- HEXAFLUOROBENZENE, NMR GRADE 1,2,3,4,5,6-Hexafluorobenzene 1,2,3,4,5,6-hexafluoro-benzene HEXAFLUOROBENZENE FOR SYNTHESIS hexafluorobenzene radical cation |
CAS | 392-56-3 |
EINECS | 206-876-2 |
InChI | InChI=1/C6F6/c7-1-2(8)4(10)6(12)5(11)3(1)9 |
Molecular Formula | C6F6 |
Molar Mass | 186.05 |
Density | 1.612 g/mL at 25 °C (lit.) |
Melting Point | 3.7-4.1 °C (lit.) |
Boling Point | 80-82 °C (lit.) |
Flash Point | 50°F |
Water Solubility | Immiscible with water. |
Vapor Presure | 94.5mmHg at 25°C |
Appearance | Liquid |
Specific Gravity | 1.612 |
Color | Clear colorless to slightly yellow |
Merck | 14,4686 |
BRN | 1683438 |
Storage Condition | Sealed in dry,Room Temperature |
Stability | Stable. Incompatible with strong oxidizing agents. May form complexes with transition metals which can explode when heated. Highly flammable. |
Refractive Index | n20/D 1.377(lit.) |
MDL | MFCD00000288 |
Risk Codes | R11 - Highly Flammable R36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S16 - Keep away from sources of ignition. S33 - Take precautionary measures against static discharges. S7/9 - S29 - Do not empty into drains. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
UN IDs | UN 1993 3/PG 2 |
WGK Germany | 3 |
RTECS | DA3050000 |
FLUKA BRAND F CODES | 10 |
TSCA | Yes |
HS Code | 29039990 |
Hazard Note | Highly Flammable |
Hazard Class | 3 |
Packing Group | II |
NIST chemical information | Information provided by: webbook.nist.gov (external link) |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
overview | perfluorobenzene is commonly used as an anesthetic and an excellent solvent for various organic substances. it is also an important intermediate for the synthesis of perfluorinated aromatic compounds and has broad application prospects in chemical industry, medicine and liquid crystal materials. |
Uses | Perfluorobenzene can be used as an important intermediate for the synthesis of perfluorinated aromatic compounds. Like benzene, perfluorobenzene can be quantitatively converted into its Dewar isomer 2 under ultraviolet irradiation, and many types of fluorocarbon compounds can be prepared by cycloaddition and other reactions using 2 as raw materials. In recent years, in the development of liquid crystal materials, it has been found that liquid crystal compounds derived from perfluorobenzene have better properties. Hexafluorobenzene is a reagent for organic synthesis, such as the preparation of polyfluoro-diaryl. It is also used in the synthesis of semiconductor polymers, such as crystal triples. |
Preparation | The earliest report on the preparation of perfluorobenzene comes from Mcbee, Lindgren, Ligett and others, who used BrF3, SbF5, and zinc powder to treat hexachlorobenzene. A small amount of perfluorobenzene can be obtained, and other by-products are perfluoro, fluorochlorine cyclohexene and cyclohexadiene compounds. Also using hexachlorobenzene as a raw material, try to use anhydrous KF to replace chlorine atoms to prepare fluorobenzene. The reaction was carried out in an autoclave at a temperature of 450~500 ℃, and finally C6F6 (yield 21%) and perfluorochlorobenzene (C6F5Cl:20%;C6F4Cl2:14%;C6F3Cl3:12%) were separated. |