hexahydro-4,7-methano-2-benzofuran-1,3-dione
Bicyclo[2.2.1]heptane-2,3-dicarboxylic Anhydride
CAS: 6004-79-1
Molecular Formula: C9H10O3
hexahydro-4,7-methano-2-benzofuran-1,3-dione - Names and Identifiers
hexahydro-4,7-methano-2-benzofuran-1,3-dione - Physico-chemical Properties
| Molecular Formula | C9H10O3 |
| Molar Mass | 166.17 |
| Density | 1.345 |
| Boling Point | 325.2°C at 760 mmHg |
| Flash Point | 158.9°C |
| Vapor Presure | 0.000233mmHg at 25°C |
| Refractive Index | 1.552 |
hexahydro-4,7-methano-2-benzofuran-1,3-dione - Introduction
Bicyclo[2.2.1]heptane-2,3-dicarboxylic Anhydride, also known as Bicyclo[2.2.1]heptane-2,3-dicarboxylic Anhydride, is an organic compound with a molecular formula of C9H10O3 and a structural formula as follows:
The properties of the compound are as follows:
-Appearance: Colorless crystalline solid.
-Melting point: about 74-78°C.
-Boiling point: about 238-240°C.
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol, ether and chloroform.
Bicyclo[2.2.1]heptane-2, the main uses of 3-dicarboxylic Anhydride include:
-As an important intermediate in organic synthesis, it is used to synthesize compounds with special structures.
-As an anhydride reagent for organic synthesis reactions, such as esterification and acyloxidation reactions.
The method of preparing Bicyclo[2.2.1]heptane-2,3-dicarboxylic Anhydride includes the following steps:
1. Dissolve cis-5-norbornane -2,3-dicarboxylic acid (Bicyclo[2.2.1]heptane-2 acid, 3-dicarboxylic acid) in an anhydrous organic solvent.
2. Add dry anhydridization reagent, such as phosphorus oxychloride (Phosphorus oxychloride) or inorganic ester (such as anhydrous hydrofluoride) at low temperature.
3. The reaction mixture is stirred under an inert atmosphere for a period of time to allow the reaction to proceed.
4. Add an appropriate amount of alcohol to react and neutralize the remaining acid to form the anhydride product.
5. The solution was filtered and crystallized to obtain the target product.
Bicyclo[2.2.1]heptane-2, the safety information of the 3-dicarboxylic Anhydride:
-This compound may cause eye, skin and respiratory tract irritation and contact should be avoided.
-When in use, wear appropriate protective equipment, such as gloves and goggles.
-Care must be taken to avoid ignition and electrostatic discharge during storage and handling, and to maintain good ventilation.
-Waste disposal shall comply with local laws and regulations.
The properties of the compound are as follows:
-Appearance: Colorless crystalline solid.
-Melting point: about 74-78°C.
-Boiling point: about 238-240°C.
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol, ether and chloroform.
Bicyclo[2.2.1]heptane-2, the main uses of 3-dicarboxylic Anhydride include:
-As an important intermediate in organic synthesis, it is used to synthesize compounds with special structures.
-As an anhydride reagent for organic synthesis reactions, such as esterification and acyloxidation reactions.
The method of preparing Bicyclo[2.2.1]heptane-2,3-dicarboxylic Anhydride includes the following steps:
1. Dissolve cis-5-norbornane -2,3-dicarboxylic acid (Bicyclo[2.2.1]heptane-2 acid, 3-dicarboxylic acid) in an anhydrous organic solvent.
2. Add dry anhydridization reagent, such as phosphorus oxychloride (Phosphorus oxychloride) or inorganic ester (such as anhydrous hydrofluoride) at low temperature.
3. The reaction mixture is stirred under an inert atmosphere for a period of time to allow the reaction to proceed.
4. Add an appropriate amount of alcohol to react and neutralize the remaining acid to form the anhydride product.
5. The solution was filtered and crystallized to obtain the target product.
Bicyclo[2.2.1]heptane-2, the safety information of the 3-dicarboxylic Anhydride:
-This compound may cause eye, skin and respiratory tract irritation and contact should be avoided.
-When in use, wear appropriate protective equipment, such as gloves and goggles.
-Care must be taken to avoid ignition and electrostatic discharge during storage and handling, and to maintain good ventilation.
-Waste disposal shall comply with local laws and regulations.
Last Update：2024-04-10 22:29:15
