hycamptamine
Topotecan
CAS: 123948-87-8
Molecular Formula: C23H23N3O5
hycamptamine - Names and Identifiers
| Name | Topotecan |
| Synonyms | hycamptamine Hycamptamine HYDROGEN CHLORIDE GAS HYDROCHLORIC ACID, 1N HYDROCHLORIC ACID,1.1M HYDROGEN CHLORIDE, BUTANOL REAGENT HYDROGEN CHLORIDE, METHANOL REAGENT HYDROGEN CHLORIDE, METHANOL REAGENT 5 HYDROGEN CHLORIDE, METHANOL REAGENT 10 9-Dimethylaminomethyl-10-hydroxycamptothecin, HCl salt |
| CAS | 123948-87-8 |
| EINECS | 687-471-1 |
| InChI | InChI=1/C23H23N3O5/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20/h5-8,27,30H,4,9-11H2,1-3H3 |
hycamptamine - Physico-chemical Properties
| Molecular Formula | C23H23N3O5 |
| Molar Mass | 421.45 |
| Density | 1.2g/mLat 25°C(lit.) |
| Melting Point | −114°C(lit.) |
| Boling Point | >100°C(lit.) |
| Flash Point | 12°C |
| Solubility | H2O: soluble |
| Vapor Presure | 613 psi ( 21.1 °C) |
| Vapor Density | 1.3 (vs air) |
| Appearance | liquid |
| Color | yellow |
| pKa | 8.92±0.40(Predicted) |
| Storage Condition | Sealed in dry,Store in freezer, under -20°C |
| Refractive Index | 1.733 |
| Physical and Chemical Properties | Topotecan Monohydrochloride: C23H23N3O5? HCl. [119413-54-6]. Solubility in water is greater than 1 mg/ml. |
| Use | Used as an antineoplastic agent |
hycamptamine - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R67 - Vapors may cause drowsiness and dizziness R35 - Causes severe burns R20 - Harmful by inhalation R11 - Highly Flammable R34 - Causes burns R48 - Danger of serious damage to health by prolonged exposure R46 - May cause heritable genetic damage R36 - Irritating to the eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S37/39 - Wear suitable gloves and eye/face protection S36 - Wear suitable protective clothing. S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S16 - Keep away from sources of ignition. S7 - Keep container tightly closed. |
| UN IDs | UN 3286 3/PG 2 |
| WGK Germany | 2 |
| RTECS | MW4025000 |
| FLUKA BRAND F CODES | 3 |
| Hazard Class | 8 |
| Packing Group | II |
hycamptamine - Nature
Open Data Verified Data
light yellow needle-like crystals or crystalline powder. Melting Point 213~218 deg C, in water solubility is greater than 1 mg/ml.
Last Update：2024-01-02 23:10:35
hycamptamine - Preparation Method
Open Data Verified Data
hydroxycamptothecin was aminomethylated with 37% formaldehyde and 40% dimethylamine in acetic acid to give the product.
Last Update：2022-01-01 09:09:11
hycamptamine - Use
Open Data Verified Data
It was developed by bicherm, Inc., and approved for marketing by the U. S. FDA in 1996. Anti-cancer drugs. It can be used alone for the treatment of metastatic ovarian cancer in which initial or continuous chemotherapy is ineffective.
Last Update：2022-01-01 09:09:12
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Product Name: Topotecan Visit Supplier Webpage Request for quotationCAS: 123948-87-8
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: SKF 104864A; NSC 609669 Visit Supplier Webpage Request for quotationCAS: 123948-87-8
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Topotecan Visit Supplier Webpage Request for quotationCAS: 123948-87-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Topotecan hydrochloride hydrate Visit Supplier Webpage Request for quotationCAS: 123948-87-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
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