Name | magnesium aluminosilicate |
Synonyms | Simagel magnesium aluminosilicate ialuminum,magnesium,dihydroxy(oxo)silane,hydrate dialuminum,magnesium,dihydroxy(oxo)silane,hydrate |
CAS | 71205-22-6 |
InChI | InChI=1/2Al.Mg.2H2O3Si.H2O/c;;;2*1-4(2)3;/h;;;2*1-2H;1H2/q2*+3;+2;; |
Molecular Formula | AlH11MgO5Si |
Molar Mass | 170.45 |
Appearance | White powder |
Storage Condition | Room Temprature |
This strain is made of kaolinite-like silica mineral powder containing high magnesium content, infiltrated with water and diluted mortar, refined, dried and crushed. The ratio of the aluminum content to the magnesium content should be 0.5 to 1.2.
take the NDJ-1 aqueous solution of this product, with type rotary viscometer, No. 2 rotor, 30 revolutions per minute, at 20°C ± 0.1T: determination according to law (General Principles 0633 second method), its dynamic viscosity is 0-3 to 0.6 * s.
Take lg of this product, add water 20ml, mix well, and determine according to law (General rule 0631),p H value should be 9.0~10. 0.
take 125g of this product, add water, control the time with a stop watch, at the same stirring speed in 5 seconds, 6 5 seconds, 185 seconds, 245 seconds, 305 seconds, seconds, 365 second, 425 second, 485 second, 545 second, 605 second, 665 second, and 725 second were added with 0.1mol/l hydrochloric acid solution 3. 0ML, added at 785 seconds. lm o l/L hydrochloric acid solution 1.0, in 840 seconds, according to the determination (General Rule 0 6 3 1 ) , the mixture of p H value should not be greater than 4 .0.
take this product, dry to constant weight at 105°C, weight loss shall not exceed 8.0% (General rule 0831).
take l .O g of this product, burn to constant weight at 700~800°C, and lose no more than 17.0% of weight.
take this product 4. 0g, add hydrochloric acid 6ml and water 30ml, heat to boiling, cool, add 2 drops of phenolphthalein indicator solution, add concentrated ammonia solution Dropwise until the solution color turns to powder red, filter, add appropriate amount of water to wash and filter, combine filtrate, add human ascorbic acid 0. 5G, and diluted with water to 50 m l, shake, take 12. 5 M l in the Nessler colorimetric tube, add acetate buffer (pH 3 .5 )2m l, diluted to 2 5 m l with water, inspected according to law (General Principles 0821 first law), containing no more than 15 parts per million of heavy metals.
take this product l .O g, add dilute hydrochloric acid 0822, boil, cool, filter, the filtrate is dried on a water bath, add hydrochloric acid 5M l and water 23ml, check according to law (General Principles first law), the provisions (0.0002%) shall be met.
This product shall be taken and inspected according to law (General Principles 1105 and 1106). The total number of aerobic bacteria per l g of test product shall not exceed lOOcfu, and the total number of molds and yeasts shall not exceed lOOcfu, E. Coli should not be detected.
take 0.5g of this product, precision weighing, add 2ml hydrochloric acid and 50ml water, boil for 3 minutes, let cool, filter, filter, filter residue and container wash with 25ml water, combine filtrate and wash, the ammonia test solution was added dropwise to precipitate the precipitate, and then dilute hydrochloric acid was added dropwise to dissolve the precipitate. 10ml of acetic acid-ammonium acetate buffer solution (pH 6.0) was added, and ethylenediamine tetraacetic acid disodium titration solution (0.0 5M o l/L )2 0M l, boil for 10 minutes, let cool, add 1ml of Xylenol Orange indicator solution, and use zinc titration solution (0. 05mol/L) titration to the solution from yellow to red, and the results of the titration with the blank test correction. Each l of ethylenediamine tetraacetic acid disodium titration solution (0.05 mol/L) is equivalent to 1. 349mg of A1.
take this product 0. 36G, precision weighing, add 3ml of hydrochloric acid and 50ml of water, boil, cool, add 1 drop of Methyl red indicator solution, add ammonia test solution to make the precipitate in the solution change from red to yellow-white, then boil for 5 minutes, while the Heat filter, filter residue and container with 2% ammonium chloride solution 30ml wash, combined filtrate and wash, cool, add ammonia test solution 10ml and triethanolamine solution (l -2)5ml, plus Chrome Black T indicator 0.3g, with ethylenediamine tetraacetic acid disodium titration solution (0.05mol/L) titration, to the solution of pure blue. Each l of ethylenediamine tetraacetic acid disodium titration solution (0.05 mol/L) is equivalent to 1.215 Mg of Mg. Calculation of the ratio of aluminum content to magnesium content shall be in accordance with the provisions.
pharmaceutical excipients, suspending agents and adsorbents.
sealed and stored in a dry cool place.
Performance | White small flake or powder, tasteless and odorless colloidal substance, soft and smooth, water content <8%. Insoluble in water or alcohol, in water can be expanded to many times larger than the original volume of colloidal dispersion. Viscosity:(5% aqueous dispersion) 0.25 · s ± 25%. Ph: (4% aqueous dispersion) about 9. 6-8ml of 0.1N HCL was required to reduce the pH of 1g of magnesium aluminum silicate to 4. The swelling properties of magnesium aluminum silicate are reversible, it can be dispersed in water, and can also be dried and rehydrated, regardless of the number of times. It is generally used in aqueous dispersions of low solids content. Stable over a wide range of pH. when magnesium aluminum silicate is dispersed in water, a colloidal sol and a gel are formed. The viscosity of the aqueous dispersion varies with the content. When the content is 1 ~ 2%, the dispersion is colloidal suspension, and when the content is> 3%, it is opaque, the viscosity increases rapidly, 4 ~ 5% is thick white Sol, when up to 10% a firm Sol was formed. Magnesium aluminum silicate is usually used in an amount of 0.5 to 2.5%. Magnesium aluminum silicate water dispersion can be very obvious denaturation. In the preparation of the dispersion, it is often necessary to appropriately heat and appropriately extend the stirring time to achieve a certain consistency. Magnesium aluminum silicate and a small amount of cellulose gum when mixed, can significantly increase the viscosity, and long-term stability. Magnesium aluminum silicate aqueous dispersion in some electrolyte thickening, and even part of the coagulation. This product is non-toxic and non-irritating. The US Food and Drug Administration (FDA) confirms that magnesium aluminum silicate is safe as a food additive and has never been prohibited from being used in internal medicine. |
Application | magnesium aluminum silicate is commonly used as a thickener, and is also a good emulsion stabilizer and suspending agent. The combination of organic glue and magnesium aluminum silicate can exert the best characteristics of both, can be used for the adhesion of different powders (talc, pigments and pharmaceutical agents), and is the disintegrant of tablets. Magnesium aluminum silicate is a hydrophilic colloid, and pseudoplastic flow properties, is cream, lotion shampoo, hair care products viscosity improver and thickener, it can be suspended and dispersed powder pigment can make the product to get the best color, the tissue was fine and smooth. As a thickening agent for toothpaste, it can be used in combination with CMC to improve the thixotropy and dispersibility of toothpaste. magnesium aluminum silicate can also be effectively used in medicine, can control the oral suspension and emulsion pouring properties, help to obtain a uniform dose of the product. It can also be used in the production of tablets. In metal and automotive polishes, tile and glass cleaners can be suspended in the friction agent and stable emulsification. For use in a white shoe polish, the suspended pigment prevents the product from becoming hard. Used in toothpaste, with natural gum, synthetic gel compatibility, can improve the structure of the strip. |