isopropyllithium
isopropyllithium
CAS: 1888-75-1
Molecular Formula: C3H7Li
isopropyllithium - Names and Identifiers
| Name | isopropyllithium |
| Synonyms | 2-Propyllithium lithium,propane 2-Lithiopropane isopropyllithium Isopropyllithium ISOPROPYLLITHIUM propan-2-yllithium lithium propan-2-ide (1-Methylethyl)lithium isopropyllithiumsolution ISOPROPYLLITHIUM, 0.7M SOLUTION IN PENTA IsopropyllithiuM solution 0.7 M in pentane |
| CAS | 1888-75-1 |
| EINECS | 217-561-4 |
| InChI | InChI=1/C3H7.Li/c1-3-2;/h3H,1-2H3;/rC3H7Li/c1-3(2)4/h3H,1-2H3 |
isopropyllithium - Physico-chemical Properties
| Molecular Formula | C3H7Li |
| Molar Mass | 50.03 |
| Density | 0.632g/mLat 25°C |
| Melting Point | 99-100℃ |
| Boling Point | 35-36°C |
| Flash Point | −31°F |
| Storage Condition | 2-8°C |
isopropyllithium - Risk and Safety
| Risk Codes | R12 - Extremely Flammable R14 - Reacts violently with water R20/22 - Harmful by inhalation and if swallowed. R34 - Causes burns R67 - Vapors may cause drowsiness and dizziness R66 - Repeated exposure may cause skin dryness or cracking R65 - Harmful: May cause lung damage if swallowed R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R11 - Highly Flammable |
| Safety Description | S16 - Keep away from sources of ignition. S33 - Take precautionary measures against static discharges. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S62 - If swallowed, do not induce vomitting; seek medical advice immediately and show this container or label. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | UN 2924 3/PG 1 |
| WGK Germany | 1 |
isopropyllithium - Introduction
isopropyllithium (also known as tertiary propyl lithium) is an organolithium compound with the chemical formula C3H7Li. The following is an introduction to the nature, use, formulation and safety information of isopropyllithium:
Nature:
- isopropyllithium is a colorless liquid with strong reducibility and alkalinity.
-It reacts quickly with water and oxygen in air, so it needs to be stored and handled under an inert gas (such as argon).
- isopropyllithium is a flammable substance that can burn when in contact with oxygen.
Use:
- isopropyllithium is mainly used in organic synthesis, for example, as a strong base reagent, reducing agent and catalyst.
-It can be used for the synthesis of lithium-containing organic compounds and metal organic compounds, and can also be used for catalytic hybrid reactions, aldol reactions and rearrangement reactions and other organic chemical reactions.
- isopropyllithium can also be used in the synthesis of certain drugs, rubber and synthetic resins.
Method:
isopropyllithium is generally obtained by reacting ethanyllithium with isopropanol:
C2H5Li (CH3)2CHOH -> C3H7Li C2H5OH
Safety Information:
- isopropyllithium has high activity and corrosiveness. Personal protective measures should be taken to avoid contact with skin, eyes and respiratory tract.
-When handling isopropyllithium, you should operate in a well-ventilated laboratory and wear personal protective equipment such as protective gloves, protective glasses and protective masks.
- isopropyllithium should be kept away from fire and oxidant. It is recommended to use inert gas for storage and store it in a corrosion-resistant container.
-In an emergency, such as a leak or fire, immediately stop using isopropyllithium, quickly evacuate the scene, and seek professional help and guidance.
Please remember that when handling chemical substances, you should strictly follow the safety procedures to ensure your own safety and the safety of the laboratory environment.
Nature:
- isopropyllithium is a colorless liquid with strong reducibility and alkalinity.
-It reacts quickly with water and oxygen in air, so it needs to be stored and handled under an inert gas (such as argon).
- isopropyllithium is a flammable substance that can burn when in contact with oxygen.
Use:
- isopropyllithium is mainly used in organic synthesis, for example, as a strong base reagent, reducing agent and catalyst.
-It can be used for the synthesis of lithium-containing organic compounds and metal organic compounds, and can also be used for catalytic hybrid reactions, aldol reactions and rearrangement reactions and other organic chemical reactions.
- isopropyllithium can also be used in the synthesis of certain drugs, rubber and synthetic resins.
Method:
isopropyllithium is generally obtained by reacting ethanyllithium with isopropanol:
C2H5Li (CH3)2CHOH -> C3H7Li C2H5OH
Safety Information:
- isopropyllithium has high activity and corrosiveness. Personal protective measures should be taken to avoid contact with skin, eyes and respiratory tract.
-When handling isopropyllithium, you should operate in a well-ventilated laboratory and wear personal protective equipment such as protective gloves, protective glasses and protective masks.
- isopropyllithium should be kept away from fire and oxidant. It is recommended to use inert gas for storage and store it in a corrosion-resistant container.
-In an emergency, such as a leak or fire, immediately stop using isopropyllithium, quickly evacuate the scene, and seek professional help and guidance.
Please remember that when handling chemical substances, you should strictly follow the safety procedures to ensure your own safety and the safety of the laboratory environment.
Last Update：2024-04-09 20:49:11
