mPEG-DSPE
mPEG-DSPE
CAS:
Molecular Formula:
mPEG-DSPE - Names and Identifiers
mPEG-DSPE - Physico-chemical Properties
| Storage Condition | -20℃ |
mPEG-DSPE - Introduction
mPEG-DSPE(mPEG-DSPE) is a complex compound with many important properties and applications.
Nature:
1. molecular formula: C37H72O12PN
2. molecular weight: about 746.94g/mol
3. Appearance: white to off-white solid
4. melting point: about 50-60 ℃
5. Solubility: Soluble in inorganic solvents and organic solvents, such as chloroform, methanol, dimethyl sulfoxide, etc.
Use:
1. Drug delivery: mPEG-DSPE can be used as a functional encapsulation material for drug nanoparticles, which can prolong the cycle life and stability of drugs by modifying the surface of drug nanoparticles, and improve the bioavailability and therapeutic effect of drugs.
2. Cell membrane simulation: mPEG-DSPE can prepare highly stable lipid nanoparticles, which can be used to simulate the structure and function of cell membrane, and study the characteristics of biological membrane and drug permeability.
3. Biological analysis: mPEG-DSPE can be used as fluorescent dyes, gold nanoparticles and other markers in the field of biological analysis, such as biological imaging, immunoassay, fluorescent probes, etc.
Preparation Method:
The synthesis of mPEG-DSPE is generally divided into two steps:
1. First, methoxy polyethylene glycol (mPEG) and distearoyl phospholipid (DSPE) are reacted in a certain molar ratio in an appropriate solvent to generate an ester-linked precursor compound.
2. Next, an amidation reaction is carried out by adding an appropriate amount of acetamide and a base to produce a mPEG-DSPE.
Security Information:
mPEG-DSPE is generally considered to be a relatively safe substance, but the following matters should be paid attention to during use:
1. Avoid direct contact with eyes, skin and mucous membranes. In case of accidental contact, rinse immediately with plenty of water.
2. in the use of the process should try to avoid inhalation of aerosol particles, in order to prevent discomfort symptoms.
3. storage and operation should avoid high temperature, direct sunlight and fire.
4. In case of accidental swallowing or discomfort, seek medical attention immediately and inform the doctor of the relevant substance.
It is worth noting that specific safety information and operating matters should refer to the safety data sheet and operating instructions provided by the manufacturer.
Nature:
1. molecular formula: C37H72O12PN
2. molecular weight: about 746.94g/mol
3. Appearance: white to off-white solid
4. melting point: about 50-60 ℃
5. Solubility: Soluble in inorganic solvents and organic solvents, such as chloroform, methanol, dimethyl sulfoxide, etc.
Use:
1. Drug delivery: mPEG-DSPE can be used as a functional encapsulation material for drug nanoparticles, which can prolong the cycle life and stability of drugs by modifying the surface of drug nanoparticles, and improve the bioavailability and therapeutic effect of drugs.
2. Cell membrane simulation: mPEG-DSPE can prepare highly stable lipid nanoparticles, which can be used to simulate the structure and function of cell membrane, and study the characteristics of biological membrane and drug permeability.
3. Biological analysis: mPEG-DSPE can be used as fluorescent dyes, gold nanoparticles and other markers in the field of biological analysis, such as biological imaging, immunoassay, fluorescent probes, etc.
Preparation Method:
The synthesis of mPEG-DSPE is generally divided into two steps:
1. First, methoxy polyethylene glycol (mPEG) and distearoyl phospholipid (DSPE) are reacted in a certain molar ratio in an appropriate solvent to generate an ester-linked precursor compound.
2. Next, an amidation reaction is carried out by adding an appropriate amount of acetamide and a base to produce a mPEG-DSPE.
Security Information:
mPEG-DSPE is generally considered to be a relatively safe substance, but the following matters should be paid attention to during use:
1. Avoid direct contact with eyes, skin and mucous membranes. In case of accidental contact, rinse immediately with plenty of water.
2. in the use of the process should try to avoid inhalation of aerosol particles, in order to prevent discomfort symptoms.
3. storage and operation should avoid high temperature, direct sunlight and fire.
4. In case of accidental swallowing or discomfort, seek medical attention immediately and inform the doctor of the relevant substance.
It is worth noting that specific safety information and operating matters should refer to the safety data sheet and operating instructions provided by the manufacturer.
Last Update：2024-04-09 21:01:54
Supplier List
Multiple Specifications
Product Name: mPEG-DSPE Visit Supplier Webpage Request for quotationTel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Multiple Specifications
Product Name: mPEG-DSPE Visit Supplier Webpage Request for quotationTel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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