mPEG-SS
mPEG-SS
CAS:
Molecular Formula:
mPEG-SS - Names and Identifiers
mPEG-SS - Physico-chemical Properties
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mPEG-SS - Introduction
mPEG-SS(mPEG-SS) is a polymer compound with the following properties:
1. physical properties: mPEG-SS is a solid, usually white or similar to white powder substance. It is soluble in water and many organic solvents at room temperature.
2. chemical properties: mPEG-SS has active thioester group, which can react with sulfide to form disulfide bond. This makes it have important applications in chemical crosslinking and drug delivery.
The main uses of mPEG-SS include the following:
1. the field of medicine: mPEG-SS is commonly used in drug delivery systems, and can achieve goal-oriented drug delivery by conjugating with ligands or modifying the structure of drugs. It can improve the solubility and stability of the drug, improve the bioavailability of the drug, and reduce the toxicity of the drug.
2. Materials science: mPEG-SS can be used to prepare polymer materials with cross-linked structure, such as hydrogels, smart materials and biomedical materials. It can provide stability, controllability and biocompatibility in these areas.
The method of preparing mPEG-SS mainly includes the following steps:
1. Esterification of methoxy-polyethylene glycol (mPEG) with diethyl thioate (thiopropionic acid) to give diethyl methoxy-polyethylene glycol succinate (mPEG-SSEt).
2. The mPEG-SSEt is reacted with a base (such as sodium hydroxide) to remove the ethyl ester group to obtain mPEG-SS.
Regarding safety information, mPEG-SS are generally considered to be relatively safe, but relevant laboratory safety regulations and operating guidelines must be followed. During use, care should be taken to ensure good ventilation conditions and avoid inhalation, chewing or contact with skin and eyes. In case of accidental contact, flush with water immediately and seek medical assistance. Please consult the safety data sheet and operating manual of the specific product before use to ensure safe operation.
1. physical properties: mPEG-SS is a solid, usually white or similar to white powder substance. It is soluble in water and many organic solvents at room temperature.
2. chemical properties: mPEG-SS has active thioester group, which can react with sulfide to form disulfide bond. This makes it have important applications in chemical crosslinking and drug delivery.
The main uses of mPEG-SS include the following:
1. the field of medicine: mPEG-SS is commonly used in drug delivery systems, and can achieve goal-oriented drug delivery by conjugating with ligands or modifying the structure of drugs. It can improve the solubility and stability of the drug, improve the bioavailability of the drug, and reduce the toxicity of the drug.
2. Materials science: mPEG-SS can be used to prepare polymer materials with cross-linked structure, such as hydrogels, smart materials and biomedical materials. It can provide stability, controllability and biocompatibility in these areas.
The method of preparing mPEG-SS mainly includes the following steps:
1. Esterification of methoxy-polyethylene glycol (mPEG) with diethyl thioate (thiopropionic acid) to give diethyl methoxy-polyethylene glycol succinate (mPEG-SSEt).
2. The mPEG-SSEt is reacted with a base (such as sodium hydroxide) to remove the ethyl ester group to obtain mPEG-SS.
Regarding safety information, mPEG-SS are generally considered to be relatively safe, but relevant laboratory safety regulations and operating guidelines must be followed. During use, care should be taken to ensure good ventilation conditions and avoid inhalation, chewing or contact with skin and eyes. In case of accidental contact, flush with water immediately and seek medical assistance. Please consult the safety data sheet and operating manual of the specific product before use to ensure safe operation.
Last Update：2024-04-09 20:02:46
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Multiple Specifications
Product Name: mPEG-SS Visit Supplier Webpage Request for quotationTel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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