mPEG2-NH2
2-(2-Methoxyethoxy)ethanamine
CAS: 31576-51-9
Molecular Formula: C5H13NO2
mPEG2-NH2 - Names and Identifiers
mPEG2-NH2 - Physico-chemical Properties
| Molecular Formula | C5H13NO2 |
| Molar Mass | 119.16 |
| Density | 0.934±0.06 g/cm3(Predicted) |
| Boling Point | 163.7±15.0 °C(Predicted) |
| Flash Point | 54.1°C |
| Solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| Vapor Presure | 2.03mmHg at 25°C |
| Appearance | Solid |
| Color | Colourless to Off-White Oil to |
| pKa | 8.75±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Stability | Hygroscopic |
| Refractive Index | 1.419 |
| In vitro study | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
mPEG2-NH2 - Risk and Safety
| UN IDs | 3265 |
| Hazard Class | 8 |
| Packing Group | Ⅱ |
mPEG2-NH2 - Reference Information
| biological activity | m-PEG2-Amine is a PROTAC connection bridge, belonging to PEG class. m-PEG2-Amine can be used to synthesize a series of PROTAC molecules. m-PEG2-Amine is a degradable (cleavable) ADC connection bridge for the synthesis of antibody drug conjugates (ADCs). |
| target | Cleavable PEGs |
| in vitro study | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
Last Update：2024-04-09 20:52:54
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CAS: 31576-51-9
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CAS: 31576-51-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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