mcn-jr-6218

Name	FLUSPIRILENE
Synonyms	Redeptin mcn-jr-6218 Fluspirilen FLUSPIRILENE Paroxetine EP IMpurity C FLUSPIRILENE (R6218) DOPAMINE ANTAGONIST 8-(4,4-bis(4-fluorophenyl)butyl)-1-phenyl-1,3,8-triazaspiro(4.5)decan-4-one R 6218, 8-[4,4-bis(p-Fluorophenyl)butyl]-1-phenyl-1,3,8-triazino[4.5]decan-4-one Fluspirilene,8-[4,4-bis(p-Fluorophenyl)butyl]-1-phenyl-1,3,8-triazino[4.5]decan-4-one, R 6218
CAS	1841-19-6
EINECS	217-418-6

Molecular Formula	C29H31F2N3O
Molar Mass	475.57
Density	1.1634 (estimate)
Melting Point	187.5-190°
Boling Point	668.9±55.0 °C(Predicted)
Solubility	DMSO: soluble
Appearance	amorphous solid
Color	white to yellow
pKa	15.05±0.20(Predicted)
Storage Condition	room temp
In vitro study	Fluspirilene, at concentrations which non-competitively modify dihydropyridine binding, selectively antagonizes the effects of calcium-channel activators. Fluspirilene decreases the viability and suppresses sphere-forming of glioma stem cell lines in a dose-dependent manner. Fluspirilene demonstrates the inhibition of proliferation of T98, U87 and all GSC lines at 1.25, 2.5, and 5 μM, while it inhibits the proliferation of U251 and SNB19 at 2.5 and 5 μM.
In vivo study	Mice treated with fluspirilene shows a remarkable reduction of the tumor size. Fluspirilene significantly prolongs survival of the TGS04 mouse model.

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Product Name: FLUSPIRILENE Visit Supplier Webpage Request for quotation
CAS: 1841-19-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

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mcn-jr-6218

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