Name | methoxatin |
Synonyms | methoxatin Methoxatine Coenzime PQQ Coenzyme PQQ Pyrroloquinoline quinone Pyrroloquinoline quinone 72909-34-3 4,5-dioxo-1H,4H,5H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid 4,5-Dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic Acid 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid PQQ Cofactor, Pyrroloquinoline quinone, 4,5-Dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid Pyrroloquinoline quinone,4,5-Dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid, Methoxatin, PQQ |
CAS | 72909-34-3 |
EINECS | 200-001-8 |
InChI | InChI=1/C14H6N2O8/c17-10-4-2-6(14(23)24)15-8(4)7-3(12(19)20)1-5(13(21)22)16-9(7)11(10)18/h1-2,15H,(H,19,20)(H,21,22)(H,23,24) |
InChIKey | MMXZSJMASHPLLR-UHFFFAOYSA-N |
Molecular Formula | C14H6N2O8 |
Molar Mass | 330.21 |
Density | 1.963±0.06 g/cm3(Predicted) |
Melting Point | 222 - 224°C |
Boling Point | 1018.6±65.0 °C(Predicted) |
Flash Point | 569.8°C |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Vapor Presure | 0mmHg at 25°C |
Appearance | Solid |
Color | Orange to Red |
BRN | 3596812 |
pKa | 1.88±0.20(Predicted) |
Storage Condition | 2-8°C |
Stability | Light and Temperature Sensitive |
Sensitive | Light and temperature sensitivity |
Refractive Index | 1.801 |
MDL | MFCD00043125 |
In vitro study | Mouse pups born to and nursing from Pyrroloquinoline quinone (PQQ)-deprived dams have a compromised immune response as well as alopecia, a hunched posture, and a susceptibility to aortic aneurysms. |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 8 |
HS Code | 29339900 |
Overview | PQQ's scientific name is pyrroloquinoline quinone, which is a new base for the treatment of heart disease, neurological diseases, protect the liver and maintain mitochondrial function. In prokaryotes, plants and mammals, there are a wide range of pyrroloquinoline quinone, it is not only the auxiliary group of many enzymes, in the enzymatic reaction is responsible for the transfer of electrons, the function of protons and chemical groups can also stimulate the growth of microorganisms, the germination of plant pollen, and promote the growth of plants. |
Application | pyrroloquinoline quinone is an important growth factor in the body; Regulate the level of free radicals, protect the body; Resist oxidative damage; enhance mitochondrial function; Detoxification; Prevent skin aging, have a weakening effect on melanin pigmentation disorders; Prevention and treatment of Parkinson's disease; Prevention and treatment of Alzheimer's disease. |
biological activity | pyrroloquinine quinone (PQQ) is a redox cofactor, an anionic redox cycle protoquinone. Pyrroloquinoline quinone was originally isolated from cultures of Methylotrophic Bacteria and is also present in mammalian tissues. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function. |