Molecular Formula | C20H22N2O3 |
Molar Mass | 338.4 |
Density | 1.273 |
Melting Point | 180-181℃ |
Boling Point | 541.1°C at 760mmHg |
Specific Rotation(α) | D26 -121.4° (chloroform) |
Solubility | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
Appearance | Cryst. |
pKa | pKa in 66% DMF: 7.5(at 25℃) |
Storage Condition | 2-8℃ |
MDL | MFCD01675246 |
In vitro study | Retinoblastoma-associated proteins (RbAp48) are related to Alzheimer's disease (AD), RbAp48 forms a complex with the peptide FOG-1 (friend of GATA-1) and has a role in gene transcription. However, this is an unstable complex may affect the function of RbAp48. Perivine has a greater stable affinity for RbAp48 binding than FOG1, it might resolve the instability of the RbAp48-FOG1 complex and thus be used in AD therapy. |