Name | Oxadixyl Sandofan |
Synonyms | Pulsan OXADIXYL Sandofan Oxadixyl metidaxyl metoxazon oxadixyl anchor 2-methoxy-n-(2-oxo-1,3-oxazolidine-3-yl)-acet-2,6-xylidine 2-methoxy-N-(2-oxo-1,3-oxazolidin-3-yl) acet-2',6'-xylidide acetamide, N-(2,6-dimethylphenyl)-2-methoxy-N-(2-oxo-3-oxazolidinyl)- Acetamide, N-(2,6-dimethylphenyl)-2-methoxy-N-(2-oxo-3-oxazolidinyl)- N-(2,6-Dimethylphenyl)-2-methoxy-N-(2-oxo-1,3-oxazolidin-3-yl)acetamid N-(2,6-Diméthylphényl)-2-méthoxy-N-(2-oxo-1,3-oxazolidin-3-yl)acétamide N-(2,6-Dimethylphenyl)-2-methoxy-N-(2-oxo-1,3-oxazolidin-3-yl)acetamide |
CAS | 77732-09-3 |
InChI | InChI=1/C14H18N2O4/c1-10-5-4-6-11(2)13(10)16(12(17)9-19-3)15-7-8-20-14(15)18/h4-6H,7-9H2,1-3H3 |
Molecular Formula | C14H18N2O4 |
Molar Mass | 278.3 |
Density | 1.1674 (rough estimate) |
Melting Point | 104-105 °C |
Boling Point | 421.12°C (rough estimate) |
Flash Point | >100°C |
Water Solubility | 3.4 mg/L at 25 ºC |
Vapor Presure | 1.27E-05mmHg at 25°C |
Appearance | neat |
Merck | 13,6976 |
BRN | 7098783 |
pKa | 1.16±0.20(Predicted) |
Storage Condition | 0-6°C |
Refractive Index | 1.5500 (estimate) |
Physical and Chemical Properties | Pure white crystals. m. P. 104-105 °c, vapor pressure 3.3 x 10-6Pa (20 °c). Solubility at 25 ° C: dimethyl sulfoxide 39.0%, acetone 34.4%, methanol 11.2%, ethanol 50%, xylene 1.7%, water 0.34%. The distribution coefficient was 4.5~6.3. Under normal storage conditions, stable to water, light and heat. |
Hazard Symbols | Xn - Harmful |
Risk Codes | 22 - Harmful if swallowed |
WGK Germany | 3 |
RTECS | AB8131400 |
Toxicity | LD50 in female rats (mg/kg): 1860 orally; >2000 dermally (Gisi) |
NIST chemical information | information provided by: webbook.nist.gov (external link) |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
toxicity | Acute Oral ld50180-3380mg/kg in rats and acute oral ld50180-2150mg/kg in mice; rat acute percutaneous LD50>2000mg/kg; Rat acute inhalation of LC50>6mg/L air (6h); No irritation to rabbit eyes and skin, no allergic to guinea pig skin. Carp LC50>300mg/L (96H), rainbow trout LC50>320mg/l (96H), pheasant acute oral LD50>2510mg/kg, acute exposure to bee LD50100 ~ 200g/only. |
Use | This product is a protective and therapeutic systemic fungicide with long lasting effect, it has a good activity against the pathogenic bacteria of the frost. The use of 250mg/L, the effective period of 9 ~ 10d, the therapeutic effect of more than 3d; With 500mg/L control of grape downy mildew, the effective period of more than 16d. The medicament is widely used to make various mixtures with other fungicides, and higher control effect can be achieved. |
production method | preparation of 2, 6-dimethylphenylhydrazine 2, 6-dimethylaniline was prepared by diazotization and reduction, 6-dimethylphenylhydrazine. Preparation of 3-(2, 6-dimethylamino) oxazolidin-2-one 2, 6-dimethylphenylhydrazine was obtained by cyclization condensation with bromopropyl chloroformate. Synthesis of oxalenin 3-(2, 6-dimethylamino) oxazolidin-2-one was prepared by the reaction of oxazolidin-2-one with 2-methoxyacetyl chloride. |