n-(hydroxymethyl)-acetamid
N-Hydroxymethylacetamide
CAS: 625-51-4
Molecular Formula: C3H7NO2
n-(hydroxymethyl)-acetamid - Names and Identifiers
| Name | N-Hydroxymethylacetamide |
| Synonyms | Acetamidomethanol ACETAMIDOMETHANOL N-ACETYLMETHANOLAMINE Hydroxymethylacetamide N-Hydroxymethylacetamide N-(HYDROXYMETHYL)ACETAMIDE N-(hydroxymethyl)acetamide HYDROXYMETHYLACETAMIDE(N-) n-(hydroxymethyl)-acetamid |
| CAS | 625-51-4 |
| EINECS | 210-897-2 |
| InChI | InChI=1/C3H7NO2/c1-3(6)4-2-5/h5H,2H2,1H3,(H,4,6) |
| InChIKey | HWJHZLJIIWOTGZ-UHFFFAOYSA-N |
n-(hydroxymethyl)-acetamid - Physico-chemical Properties
| Molecular Formula | C3H7NO2 |
| Molar Mass | 89.09 |
| Density | 1.14 |
| Melting Point | 48-52°C |
| Boling Point | 165.17°C (rough estimate) |
| Flash Point | 148.1°C |
| Water Solubility | Soluble |
| Solubility | Chloroform (Sparingly, Sonicated), DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 2.41E-05mmHg at 25°C |
| Appearance | Crystalline |
| Color | White to Off-White Low-Melting |
| Merck | 14,4242 |
| BRN | 506226 |
| pKa | 13.28±0.10(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Sensitive | Hygroscopic |
| Refractive Index | 1.4368 (estimate) |
| MDL | MFCD00014417 |
n-(hydroxymethyl)-acetamid - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| RTECS | AC3610000 |
| FLUKA BRAND F CODES | 10 |
| Hazard Class | IRRITANT |
n-(hydroxymethyl)-acetamid - Introduction
N-Hydroxymethylacetamide(N-Hydroxymethylacetamide) is an organic compound. It is obtained by substitution of hydroxymethyl groups on the acetamide molecule. Its chemical formula is CH3CONHCH2OH.
N-Hydroxymethylacetamide is a colorless to light yellow liquid, soluble in common organic solvents, such as water, ethanol and ether. It is a relatively stable compound that is not easily decomposed or inactivated.
N-Hydroxymethylacetamide have some applications in the chemical and biological sciences. It can be used as a reagent in organic synthesis for the synthesis of other compounds or ligands. In addition, it can also be used as a complexing agent for metal ions to help form coordination compounds in catalytic reactions.
The method of preparing N-Hydroxymethylacetamide is usually through the reaction of acetaldehyde and methanol to produce methylacetamide, which is then converted into N-Hydroxymethylacetamide through an oxidation reaction.
When using N-Hydroxymethylacetamide, you need to pay attention to its safety. Although it does not pose a significant risk under routine experimental conditions, as an organic compound, it may still have some toxic or irritating effects on the human body. Therefore, the use of safety procedures should be followed, and take appropriate protective measures, such as wearing gloves, goggles and protective clothing.
N-Hydroxymethylacetamide is a colorless to light yellow liquid, soluble in common organic solvents, such as water, ethanol and ether. It is a relatively stable compound that is not easily decomposed or inactivated.
N-Hydroxymethylacetamide have some applications in the chemical and biological sciences. It can be used as a reagent in organic synthesis for the synthesis of other compounds or ligands. In addition, it can also be used as a complexing agent for metal ions to help form coordination compounds in catalytic reactions.
The method of preparing N-Hydroxymethylacetamide is usually through the reaction of acetaldehyde and methanol to produce methylacetamide, which is then converted into N-Hydroxymethylacetamide through an oxidation reaction.
When using N-Hydroxymethylacetamide, you need to pay attention to its safety. Although it does not pose a significant risk under routine experimental conditions, as an organic compound, it may still have some toxic or irritating effects on the human body. Therefore, the use of safety procedures should be followed, and take appropriate protective measures, such as wearing gloves, goggles and protective clothing.
Last Update：2024-04-10 22:29:15
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CAS: 625-51-4
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Mobile: 18021002903
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