p-Nitrobenzamide
4-Nitrobenzamide
CAS: 619-80-7
Molecular Formula: C7H6N2O3
p-Nitrobenzamide - Names and Identifiers
| Name | 4-Nitrobenzamide |
| Synonyms | 4-Nitrobenzamide p-Nitrobenzamide 4 Nitro Benzamide |
| CAS | 619-80-7 |
| EINECS | 210-613-7 |
| InChI | InChI=1/C7H6N2O3/c8-7(10)5-1-3-6(4-2-5)9(11)12/h1-4H,(H2,8,10) |
p-Nitrobenzamide - Physico-chemical Properties
| Molecular Formula | C7H6N2O3 |
| Molar Mass | 166.134 |
| Density | 1.384g/cm3 |
| Melting Point | 198-202℃ |
| Boling Point | 368°C at 760 mmHg |
| Flash Point | 176.3°C |
| Water Solubility | <0.01 g/100 mL at 18℃ |
| Vapor Presure | 1.32E-05mmHg at 25°C |
| Refractive Index | 1.612 |
| Use | Used as pharmaceutical and dye intermediates |
p-Nitrobenzamide - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed |
p-Nitrobenzamide - Introduction
4-Nitrobenzamide(4-Nitrobenzamide) is an organic compound with the chemical formula of C7H6N2O3, which is a yellow crystalline powder.
The main properties of 4-Nitrobenzamide include:
-density: 1.45 g/cm ^ 3
-Solubility: Slightly soluble in water, soluble in alcohol and ketone solvents
-melting point: 136-139 ℃
-Thermal stability: thermal stability
The main uses of 4-Nitrobenzamide include:
-As an intermediate in organic synthesis: It can be used to synthesize other organic compounds, such as drugs and dyes.
-As a scientific research reagent: used for certain reactions in analytical chemistry and organic chemistry laboratories.
The preparation of 4-Nitrobenzamide can generally be achieved through the following steps:
1. Add p-nitroaniline (4-Nitroaniline) and excess formic acid to the reactor.
2. Stir the reactants at an appropriate temperature and add a basic catalyst.
3. After a certain reaction time, the product is appropriately extracted and purified.
For the safety information of 4-Nitrobenzamide, the following points should be noted:
- 4-Nitrobenzamide may cause irritation to the skin, eyes, and respiratory tract and should be avoided.
-Wear appropriate personal protective equipment such as safety glasses, gloves and protective clothing during operation.
-It should be operated in a well-ventilated place and away from fire and heat sources.
-During storage and transportation, care should be taken to avoid reactions with other chemicals.
-When you smell or come into contact with 4-Nitrobenzamide abnormally, you should stop using it immediately and seek medical help.
This information is for reference, please use and handle 4-Nitrobenzamide correctly according to the actual situation.
The main properties of 4-Nitrobenzamide include:
-density: 1.45 g/cm ^ 3
-Solubility: Slightly soluble in water, soluble in alcohol and ketone solvents
-melting point: 136-139 ℃
-Thermal stability: thermal stability
The main uses of 4-Nitrobenzamide include:
-As an intermediate in organic synthesis: It can be used to synthesize other organic compounds, such as drugs and dyes.
-As a scientific research reagent: used for certain reactions in analytical chemistry and organic chemistry laboratories.
The preparation of 4-Nitrobenzamide can generally be achieved through the following steps:
1. Add p-nitroaniline (4-Nitroaniline) and excess formic acid to the reactor.
2. Stir the reactants at an appropriate temperature and add a basic catalyst.
3. After a certain reaction time, the product is appropriately extracted and purified.
For the safety information of 4-Nitrobenzamide, the following points should be noted:
- 4-Nitrobenzamide may cause irritation to the skin, eyes, and respiratory tract and should be avoided.
-Wear appropriate personal protective equipment such as safety glasses, gloves and protective clothing during operation.
-It should be operated in a well-ventilated place and away from fire and heat sources.
-During storage and transportation, care should be taken to avoid reactions with other chemicals.
-When you smell or come into contact with 4-Nitrobenzamide abnormally, you should stop using it immediately and seek medical help.
This information is for reference, please use and handle 4-Nitrobenzamide correctly according to the actual situation.
Last Update：2024-04-09 19:05:51
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