Use | (4-nitrophenyl) potassium trifluoroborate can be used as an intermediate in pharmaceutical synthesis. For example, it can be used to synthesize diaryl sulfone compounds. It is prepared by reacting 4-bromonitrobenzene as the reaction raw material with tetramethylaminoborane and potassium hydrogen fluoride. (4-nitrophenyl) potassium trifluoroborate, also known as potassium p-nitrophenyl fluoroborate, is an organic intermediate that can be used to prepare diaryl sulfone catalyzed by cuprous chloride at room temperature. As a pharmaceutical and pesticide intermediate, diaryl sulfone compounds are commonly used in organic synthesis and have shown good biological activities. For example, diaryl sulfone has been proved to have antifungal, antibacterial and antitumor activities. Recently, diaryl sulfone and aromatic heterocyclic sulfone have been proved to inhibit HIV-1 reverse transcriptase, representing a new class of substances that can solve the problem of drug residual toxicity and drug resistance of nucleoside inhibitors. |