potassiumazaorotate
oxonic acid potassium salt
CAS: 2207-75-2
Molecular Formula: C4H2KN3O4
potassiumazaorotate - Names and Identifiers
potassiumazaorotate - Physico-chemical Properties
| Molecular Formula | C4H2KN3O4 |
| Molar Mass | 195.17 |
| Melting Point | 300°C(lit.) |
| Water Solubility | Soluble in hot water. |
| Solubility | Dissolve in hot water. |
| Appearance | White crystal |
| Color | White |
| Storage Condition | Inert atmosphere,2-8°C |
| MDL | MFCD00010565 |
| Physical and Chemical Properties | White crystalline powder |
potassiumazaorotate - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| RTECS | RR4580000 |
| HS Code | 29349990 |
potassiumazaorotate - Reference
| Reference Show more | 1. Lu Cunlong, Li Yu, Li Long et al. Effects of Roux-en-Y Gastric Bypass Surgery and Sleeve Gastrectomy on Metabolism in Hyperuricemia Rats and Its Mechanism [J]. Chinese Journal of Obesity and Metabolic Diseases 2017 3(4):198-207. 2. Wang Zeci Xiaoyan Cui Tao Wei Zihong Zhang Hongbing Liu Rui Li Yazhuo Yi Xiulin Zhang Tiejun Gu Yuan Wuwei Party Liu Changxiao. Inhibitory effects of different medicinal components on OAT4 and URAT1 and their effects on serum uric acid level in acute hyperuricemia mice [J]. Chinese herbal medicine 2019 50(05):1157-1163. 3. Yang Xuefang Gao Koli Wang Yongchang et al. Effects of Different Extracts of Modified Siwu Suteng Decoction on Blood Uric Acid and Xanthine Oxidase in Rats [J]. Chinese Journal of Traditional Chinese Medicine Information 2014 21(011):66-68. 4. Liu Jing, Liu Mei, Yang Bo, etc. Effects of Rehmannia glutinosa Extract on Hyperuricemia Mice [J]. China Drug Application and Monitoring, 2015, v.12;No.70(06):347-350. 5. Li Yuanyuan, Zhou Haiyan, Wu Luying, et al. Establishment and Research of Rat Hyperuricemia Model [J]. Chinese Journal of Experimental Animals, 2019, 027(006):747-752. 6. Shi Tuo, Lu Cunlong, Li Long, et al. Study on Serum Metabolomics of Hyperuricemia Rats by Liquid Chromatography-Mass Spectrometry [J]. Basic Medicine and Clinic, 2019, V39(03):337-342. 7. Wang Miaohui, Ma Hongbin, Sun Hongxu, et al. Effect of Qingre Paidu Capsule on Uric Acid and Xanthine Oxidase in Hyperuricemia Rats [J]. Guangming Traditional Chinese Medicine, 2014(05):950-952. 8. Wang Lu, kanna, Zhao Bo, et al. Effects of total flavonoids from burdock root on hyperuricemia mice [J]. Journal of Northwest University (Natural Science Edition), 2019(5). 9. Zhang Ya, Wang Yiqiao, Ma Zhuoya, et al. Pharmacodynamic experiment combined with orthogonal test to optimize the water extraction and alcohol precipitation process of Zhuang Yao Baijin Granules [J]. China Pharmacy, 2020, v.31;No.674(08):28-34. 10. Wu Gao, Wu Hanbin, Jiang Hong. Study on uric acid-lowering effect of polydatin and its mechanism [J]. Journal of Pharmacy, 2014(12):1739-1742. 11. Yu Junjun, Xu Deping. Uric acid-lowering efficacy components of Hovenia dulcis Thunb [J]. Food Science and Technology, 2019, v.44;No.337(11):234-238 244. 12. Xing Zhihua, bao Ran, Jiang Jingwen, et al. Synthesis of apigenin-samarium complex and its anti-hyperuricemia in mice. Research and development of natural products. 13. Shi Hui, Liang Xiaoshan, Huang Liwen, Luo Zhigang, Tan Long. Electrolytic drinking water promotes uric acid metabolism in hyperuricemia SD rats [J]. Health Research, 2020,49(05):802-808. 14. Kangle, Miao Jinxin, Miao Mingsan, Liu Huijuan, Li Ning. Pharmacodynamic Mechanism of Paeonia lactiflora Total Glycosides on Hyperuricemia Model in Mice [J]. Shi Zhen Chinese Medicine, 2020,31(08):1844-1846. 15. Huang Liulu, Mei Jie, Pan Li, Wang Huimin, Li Fang, Zhang Yuanyuan, Kou Junping, Yu Boyang. Study on the Effect of Soda Water on Uric Acid Reduction [J]. Modern Food, 2020(22):164-169 173. 16. Xu Mengqi, Xu Deping. Study on Uric Acid Reduction Active Components of Smilax glabra [J]. Research and development of natural products, 2020,32(11):1860-1865. 17. Guo, Lin-Feng, et al. "Effects and mechanisms of Dendrobium officinalis six nostrum for treatment of Hyperuricemia with hyperlipidemia." Evidence-Based Complementary and Alternative Medicine 2020 (2020).https://doi.org/10.1155/2020/2914019 18. Yun, Yu, et al. "Intestinal tract is an important organ for lowering serious acid in rats." PloS one 12.12 (2017): e0190194.https://doi.org/10.1371/journal.pone.0190194 19. [IF = 2.74] Yu Yun et al. "Intestinal tract is an important organ for lowering serious acid in rats." Plos One. 2017 Dec;12(12): e0190194 20. [IF = 4.411] Xiaoke Wang et al. "Novel Carbon Dots Derived from Puerariae lobatae Radix and Their Anti-Gout Effects." Molecules. 2019 Jan;24(22):4152 21. [IF = 3.981] Wenhao Xu et al. "Self-assembled nanocapsules of celery (Apium graveolens Linn) seed oil: Mechanochemical preparation, characterization and urate-lowering activity." J Drug Deliv Sci Tec. 2021 Dec;66:102810 22. [IF = 2.629] Guo Lin-Feng et al. "Effects and Mechanisms of Dendrobium officinalis Six Nostrum for Treatment of Hyperuricemia with Hyperlipidemia." Evid-Based Compl Alt. 2020;2020:2914019 23. [IF = 2.629] Yao Rongmei et al. "Tu-Teng-Cao Extract Alleviates Monosodium Urate-Induced Acute Gouty Arthritis in Rats by Inhibiting Uric Acid and Inflammation." Evid-Based Compl All. 2020;2020:3095624 24. [IF = 6.543] Liu Lijun et al. "Inflammatory Response and Oxidative Stress as Mechanism of Reducing Hyperuricemia of Gardenia jasminoides-Poria cocos with Network Pharmacology." Oxid Med Cell Longev. 2021;2021:8031319 |
potassiumazaorotate - Reference Information
| Biological activity | Potassium oxonate are uricase inhibitors that can inhibit 5-FU phosphorylation to 5-fluorouridine-5 '-monophosphate. |
| use | anticancer drug S-1 one component, which can inhibit the toxic and side effects of antitumor drug tegafur |
| category | toxic substances |
| toxicity classification | highly toxic |
| acute toxicity | non-intestinal-human TDL0: 20 mg/kg |
| flammability hazard characteristics | combustible; combustion produces toxic nitrogen oxides and potassium oxide smoke |
| storage and transportation characteristics | warehouse ventilation and low temperature drying; separate from food raw materials |
| fire extinguishing agent | dry powder, foam, sand, carbon dioxide, mist water |
Last Update：2024-04-09 21:01:54
Supplier List
Featured ProductsSpot supply
Product Name: Potassium oxonate Visit Supplier Webpage Request for quotationCAS: 2207-75-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: oxonic acid potassium salt Request for quotationCAS: 2207-75-2
Tel: 86+027-83389957
Email: 1024042217@qq.com
Mobile: 86+18627766980
QQ: 1024042217
Wechat: 18627766980
Product Name: Potassium oxyzinate Request for quotation
CAS: 2207-75-2
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: 13651600618
WhatsApp: +8613651600618
CAS: 2207-75-2
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: 13651600618
WhatsApp: +8613651600618
Featured ProductsSpot supply
Product Name: Potassium oxonate Visit Supplier Webpage Request for quotationCAS: 2207-75-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: oxonic acid potassium salt Request for quotationCAS: 2207-75-2
Tel: 86+027-83389957
Email: 1024042217@qq.com
Mobile: 86+18627766980
QQ: 1024042217
Wechat: 18627766980
Product Name: Potassium oxyzinate Request for quotation
CAS: 2207-75-2
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: 13651600618
WhatsApp: +8613651600618
CAS: 2207-75-2
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: 13651600618
WhatsApp: +8613651600618
View History