protostemotinine
protostemotinine
CAS: 169534-85-4
Molecular Formula: C23H29NO6
protostemotinine - Names and Identifiers
| Name | protostemotinine |
| Synonyms | ProtosteMotinine protostemotinine (3S,11S,11aS)-3'-Methoxy-4',9-dimethyl-3-[(2S,4S)-4-methyl-5-oxotetrahydrofuran-2-yl]-2,3,5,6,7,8-hexahydro-1H,5'H,10H-spiro[cyclopenta[b]pyrrolo[1,2-a]azepine-11,2'-furan]-5',10-dione (3S,11S,11aS)-3'-Methoxy-4',9-dimethyl-3-[(2S,4S)-4-methyl-5-oxot etrahydro-2-furanyl]-2,3,5,6,7,8-hexahydro-1H,5'H,10H-spiro[cyclo penta[b]pyrrolo[1,2-a]azepine-11,2'-furan]-5',10-dione Spiro[1H-cyclopenta[b]pyrrolo[1,2-a]azepine-11(10H),2'(5'H)-furan]-5',10-dione, 2,3,5,6,7,8-hexahydro-3'-methoxy-4',9-dimethyl-3-[(2S,4S)-tetrahydro-4-methyl-5-oxo-2-furanyl]-, (2'S,3S,11aS)- spiro[1H-cyclopenta[b]pyrrolo[1,2-a]azepine-11(10H),2'(5'H)-furan]-5',10-dione, 2,3,5,6,7,8-hexahydro-3'-methoxy-4',9-dimethyl-3-[(2S,4S)-tetrahydro-4-methyl-5-oxo-2-furanyl]-, (3S,11S,11aS)- |
| CAS | 169534-85-4 |
| InChI | InChI=1/C23H29NO6/c1-12-11-17(29-20(12)26)16-8-9-22-15(7-5-6-10-24(16)22)13(2)18(25)23(22)19(28-4)14(3)21(27)30-23/h12,16-17H,5-11H2,1-4H3/t12-,16-,17-,22-,23+/m0/s1 |
protostemotinine - Physico-chemical Properties
| Molecular Formula | C23H29NO6 |
| Molar Mass | 415.48 |
| Density | 1.31±0.1 g/cm3 (20 ºC 760 Torr) |
| Boling Point | 690.7±55.0 °C at 760 mmHg |
| Solubility | Slightly soluble (3.9g/L) (25°C) |
| Appearance | White crystalline powder |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.59 |
| MDL | MFCD14155631 |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Baibu. |
protostemotinine - Reference Information
| interaction | 1. combined with baixiaoamine, cyclophosphamide, methotrexate, glorimycin, hydralazine, hexahydroxyquaternary, mecamin, nitrofurantoin, ercoxonine, oral contraceptives, chlorothiazide and butazone, etc., can aggravate dyspnea. 2. combined with ferrous sulfate, sulfa, aminophylline, acidogenic drugs, digitalis and levodopa, can cause nausea and vomiting. |
| adverse reactions | 1. toxic reactions: nausea and vomiting, abdominal pain, diarrhea, epistaxis, biliary colic, dizziness, headache, pale complexion, dyspnea, etc. are occasionally seen after oral administration. In severe cases, convulsions, coma, and even death due to paralysis of the respiratory center may occur. 2. allergic reaction: small red miliary rash appeared on the skin, itching is unbearable. |
| biological activity | Protostemotinine is an alkaloid isolated from Stemona sessilifolia. |
| chemical properties | white crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Baibu. |
| use | protopepenobase has anti-inflammatory, anti-inflammatory and anti-allergic effects. |
Last Update：2024-04-09 20:49:11
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