rac-(3R*)-Pyrrolidine-3-ol - Names and Identifiers
Name | Pyrrolidinol
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Synonyms | pyrrolidinol Pyrrolidinol DL-3-Pyrrolidinol DL-3-PYRROLIDINOL 3-HYDROXYPYRROLINE rac-Pyrrolidine-3α*-ol DL-3-HYDROXYPYRROLIDINE rac-(3R*)-Pyrrolidine-3-ol (3as,3bs,5ar,7r,9as,9bs,11as)-2-amino-7-hydroxy-9a,11a-dimethyl-3,3a,3b,4,5,5a,6,7,8,9,9a,9b,11,11a-tetradecahydro-10h-naphtho[2,1-e]indol-10-one
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CAS | 83220-72-8
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EINECS | 672-215-3 |
rac-(3R*)-Pyrrolidine-3-ol - Physico-chemical Properties
Molecular Formula | C4H9NO
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Molar Mass | 87.12 |
Density | 1.076g/mLat 20°C(lit.) |
Boling Point | 108-110°C8mm Hg(lit.) |
Flash Point | >230°F |
Specific Gravity | 1.08 |
Refractive Index | n20/D 1.49(lit.) |
rac-(3R*)-Pyrrolidine-3-ol - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37 - Wear suitable gloves.
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WGK Germany | 3 |
FLUKA BRAND F CODES | 10-34 |
Hazard Class | IRRITANT |
rac-(3R*)-Pyrrolidine-3-ol - Introduction
Pyrrolidinol(Pyrrolidinol) is an organic compound, its chemical formula is C4H9NO, is an alcohol compound.
Regarding the nature of the Pyrrolidinol, it is a colorless to light yellow liquid with a special smell. It is soluble in many organic solvents, such as ethanol, dimethylformamide and acetonitrile. It can react lightly with oxygen air at conventional pressures and reacts readily with anhydrides or anhydride derivatives.
One of the main uses of Pyrrolidinol is as an intermediate for the synthesis of organic compounds, especially in drug synthesis. It can be used as a starting material for the synthesis of natural compounds and drugs, such as certain anticancer drugs, such as cyclophosphamide and ifosfamide.
Regarding the production method, the Pyrrolidinol can be obtained by catalytic hydrogenation of pyrrolylacetic acid with hydrogen. First, pyrrolylacetic acid is reacted with hydrogen at an appropriate temperature and pressure in the presence of a catalyst to produce Pyrrolidinol. The preparation process needs to pay attention to control the appropriate reaction conditions to obtain high yield and purity.
From a safety perspective, Pyrrolidinol are generally safe under normal conditions of use. However, as an organic compound, it may cause irritation and toxicity to the human body. Therefore, appropriate safe operating procedures should be observed during handling and use, including the wearing of appropriate protective equipment (such as gloves and goggles). In addition, it should be operated in a well-ventilated area to avoid inhalation or exposure to high concentrations of vapors or liquids.
Last Update:2024-04-09 21:54:55