squalamine

Name	squalamine
Synonyms	MSI 1256 squalamine Cholestane-7,24-diol,3-[[3-[(4-aminobutyl)amino]propyl]amino]-, 24-(hydrogen sulfate), (3b,5a,7a,24R)- Cholestane-7,24-diol, 3-[[3-[(4-aminobutyl)amino]propyl]amino]-, 24-(hydrogen sulfate), (3β,5α,7α,24R)-
CAS	148717-90-2

Molecular Formula	C34H65N3O5S
Molar Mass	627.96
Density	1.13±0.1 g/cm3(Predicted)
pKa	-3.49±0.18(Predicted)
Storage Condition	2-8℃
Physical and Chemical Properties	Soluble in water.

Last Update：2024-01-02 23:10:35

biological activity	Squalamine(MSI-1256) is a compound with broad-spectrum antiviral activation.
Use	a broad-spectrum antimicrobial of aminosterols present in shark tissues. It is a novel indicator of steroids as host defense agents in vertebrates.
production method	Method 1: isolated from the stomach of a spiny horn shark and a sea-green horn shark. Method 2: Synthesis of 3-hydroxy -5-bile acid (3 beta-hydroxy-5-hydroxy acid), Chenodeoxycholic acid (Chenodeoxycholic acid), fucosterol (fucosterol 1), Dehydroepiandrosterone (Dehydroepiandrosterone) or vinyl alcohol ketone Acetate (pregnen alone Acetate) as a raw material to prepare. For example, the compound (I) can be obtained by a 12-step reaction using 3 β-hydroxy-5-cholic acid as a starting material, and the product is obtained by the following reaction. Hydrochloric acid acidification of Squalamine trihydrochloride.

Last Update：2024-04-09 21:04:16

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CAS: 148717-90-2
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squalamine

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