tert-Butyl-3-cyanpyrrolidin-1-carboxylate
1-Boc-3-cyanopyrrolidine
CAS: 476493-40-0
Molecular Formula: C10H16N2O2
tert-Butyl-3-cyanpyrrolidin-1-carboxylate - Names and Identifiers
tert-Butyl-3-cyanpyrrolidin-1-carboxylate - Physico-chemical Properties
| Molecular Formula | C10H16N2O2 |
| Molar Mass | 196.25 |
| Density | 1.08±0.1 g/cm3(Predicted) |
| Boling Point | 307.9±35.0 °C(Predicted) |
| Flash Point | 140°C |
| Vapor Presure | 0.000703mmHg at 25°C |
| pKa | -3.73±0.40(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.488 |
| MDL | MFCD03001709 |
tert-Butyl-3-cyanpyrrolidin-1-carboxylate - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | 3439 |
| Hazard Class | 6.1 |
| Packing Group | III |
tert-Butyl-3-cyanpyrrolidin-1-carboxylate - Introduction
1-Boc-3-cyanopyrrolidine(1-Boc-3-cyanopyrrolidine) is an organic compound. It has a molecular formula of C11H17NO3 and a molecular weight of 215.26g/mol. It is a colorless to pale yellow solid and has an aroma.
The compound has a variety of uses. First, it can be used as an important intermediate in organic synthesis. It can be used for the synthesis of various drugs and other compounds, for example for the synthesis of antiviral drugs, anticancer drugs and antibiotics, etc. In addition, it can also be used as a chiral reagent and a catalyst.
The method for preparing 1-Boc-3-cyanopyrrolidine is relatively simple. The commonly used method is to react 3-cyanopyrrolidine and tert-butyl magnesium bromide to obtain the corresponding carboxylic acid, then carry out the anhydride reaction, and finally treat with alkali to obtain the target product.
Regarding safety information, 1-Boc-3-cyanopyrrolidine is relatively safe under normal conditions of use. However, like most organic compounds, it has a certain irritation and toxicity. When handling, good laboratory practices and safety practices should be observed, including wearing appropriate personal protective equipment to prevent contact with skin, eyes and respiratory tract. Avoid inhaling aerosols or eating them by mistake during use. If necessary, it should be used in a well-ventilated place and avoid reaction with oxidants and strong acids/bases.
The information mentioned here is for reference only. Please consult relevant literature and safety materials in detail before use, and follow appropriate operating guidelines and regulations.
The compound has a variety of uses. First, it can be used as an important intermediate in organic synthesis. It can be used for the synthesis of various drugs and other compounds, for example for the synthesis of antiviral drugs, anticancer drugs and antibiotics, etc. In addition, it can also be used as a chiral reagent and a catalyst.
The method for preparing 1-Boc-3-cyanopyrrolidine is relatively simple. The commonly used method is to react 3-cyanopyrrolidine and tert-butyl magnesium bromide to obtain the corresponding carboxylic acid, then carry out the anhydride reaction, and finally treat with alkali to obtain the target product.
Regarding safety information, 1-Boc-3-cyanopyrrolidine is relatively safe under normal conditions of use. However, like most organic compounds, it has a certain irritation and toxicity. When handling, good laboratory practices and safety practices should be observed, including wearing appropriate personal protective equipment to prevent contact with skin, eyes and respiratory tract. Avoid inhaling aerosols or eating them by mistake during use. If necessary, it should be used in a well-ventilated place and avoid reaction with oxidants and strong acids/bases.
The information mentioned here is for reference only. Please consult relevant literature and safety materials in detail before use, and follow appropriate operating guidelines and regulations.
Last Update：2024-04-09 21:54:55
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Product Name: 1-Boc-3-cyanopyrrolidine Visit Supplier Webpage Request for quotation
CAS: 476493-40-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 476493-40-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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