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tert-butyl (2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)carbamate

tert-butyl (2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)carbamate

CAS: 869310-84-9

Molecular Formula: C12H21NO4

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tert-butyl (2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)carbamate - Names and Identifiers

Name tert-butyl (2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)carbamate
Synonyms Propargyl-PEG2-NHBoc
t-Boc-N-Amido-PEG2-Propargyl
N-Boc-2-[2-(2-propyn-1-yloxy)ethoxy]ethanamine
tert-butyl (2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)carbamate
CAS 869310-84-9

tert-butyl (2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)carbamate - Physico-chemical Properties

Molecular FormulaC12H21NO4
Molar Mass243.3
Physical and Chemical PropertiesBioactive Propargyl-PEG2-NHBoc is a degradable (cleavable) ADC linker used in the synthesis of antibody-coupled drugs (ADCs). Propargyl-PEG2-NHBoc is a PROTAC linker and belongs to the PEG class. Propargyl-PEG2-NHBoc can be used to synthesize a series of PROTAC molecules.
In vitro study ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

tert-butyl (2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)carbamate - Uses and synthesis methods

Target

CleavablePEGsAlkyl/ether

in vitro studies

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Last Update:2024-04-10 22:29:15

tert-butyl (2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)carbamate - Introduction

tert-butyl (2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)carbamate is an organic compound. The following is an introduction to some of its properties, uses, formulation and safety information:

Nature:
- tert-butyl (2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)carbamate is a colorless liquid with an odor similar to acetate.
-It is soluble in organic solvents such as alcohols and ethers.

Use:
- tert-butyl (2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)carbamate is usually used as a synthetic intermediate to prepare other chemical compounds.
-It can be used as acylation reagent and cyclization reagent in chemical synthesis.

Preparation Method:
-The preparation method of tert-butyl (2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)carbamate generally involves chemical reactions and synthetic steps. The specific preparation method may vary depending on the purpose of the study.

Safety Information:
- tert-butyl (2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)carbamate may be irritating. In operation and use, should follow the correct safety laboratory and chemical use guidelines.
-In any case, avoid direct contact with skin and eyes, and avoid inhaling its vapor or dust.
-It should be stored in a dry, cool, well-ventilated place, and away from combustibles and heat sources.

Please note that this is only an overview, and specific chemical and safety information should be studied and understood in a laboratory or professional environment.
Last Update:2024-04-09 19:05:03
tert-butyl (2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)carbamate
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CAS: 869310-84-9
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Product Name: tert-butyl (2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)carbamate Visit Supplier Webpage Request for quotation
CAS: 869310-84-9
Tel: +86-18821248368
Email: Int06@meryer.com
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QQ: 495145328 Click to send a QQ message
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View History
tert-butyl (2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)carbamate
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氰化异戊烷
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