tert-butyl 5-amino-1H-indole-1-carboxylate - Names and Identifiers
tert-butyl 5-amino-1H-indole-1-carboxylate - Physico-chemical Properties
Molecular Formula | C13H16N2O2
|
Molar Mass | 232.28 |
Density | 1.16±0.1 g/cm3(Predicted) |
Boling Point | 384.2±34.0 °C(Predicted) |
pKa | 4.28±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
tert-butyl 5-amino-1H-indole-1-carboxylate - Introduction
1-Boc-5-aminoindole is an organic compound with the chemical formula C16H19N3O2.
Nature:
1-Boc-5-aminoindole is a white crystal with a faint ammonia odor. Its melting point is about 85-88°C. The compound is soluble in some organic solvents such as dimethyl sulfoxide (DMSO) and chloroform.
Use:
1-Boc-5-aminodole is an important intermediate, usually used in the synthesis of indole derivatives in organic synthesis. Indole has a wide range of biological activities and can be used to develop new drugs, pesticides and other organic compounds.
Preparation Method:
The common method of preparing 1-Boc-5-aminoindole is through the reaction of 1-Boc-5-chloroindole. A specific preparation method may be to react 1-Boc-5-chloroindole with ammonia to obtain 1-Boc-5-aminoindole. The reaction is typically carried out under basic conditions and may require appropriate solvents and temperatures.
Safety Information:
1-Boc-5-aminoindole is less toxic and dangerous, but appropriate protective measures should still be taken. Wear appropriate personal protective equipment such as gloves, glasses and protective clothing during use and handling. Avoid direct contact with skin and eyes. At the same time, the working environment should be well ventilated. During storage and transportation, high temperature and fire sources should be avoided.
Last Update:2024-04-09 21:11:58