trans-1-Amino-4-(hydroxymethyl)cyclohexane

trans-1-Amino-4-(hydroxymethyl)cyclohexane - Names and Identifiers

Name	trans-4-Aminocyclohexanemethanol
Synonyms	, trans- Aminocyclohexanemethanol trans-4-Aminocyclohexanemethanol (trans-4-Aminocyclohexyl)methanol ((1R,4r)-4-aMinocyclohexyl)Methanol Cyclohexanemethanol, 4-amino-, trans- trans-1-Amino-4-(hydroxymethyl)cyclohexane
CAS	1467-84-1
InChI	InChI=1/C7H15NO/c8-7-3-1-6(5-9)2-4-7/h6-7,9H,1-5,8H2/t6-,7-

trans-1-Amino-4-(hydroxymethyl)cyclohexane - Physico-chemical Properties

Molecular Formula	C7H15NO
Molar Mass	129.2
Density	0.974±0.06 g/cm3(Predicted)
Melting Point	146-148?C
Boling Point	218.8±13.0 °C(Predicted)
Solubility	Chloroform, Dichloromethane, Methanol
Appearance	Solid
Color	White to Off-White
pKa	15.05±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,2-8°C
Refractive Index	1.477

trans-1-Amino-4-(hydroxymethyl)cyclohexane - Introduction

trans-4-Aminocyclohexanemethanol, also known as p-Aminocyclohexylmethanol, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
trans-4-Aminocyclohexanemethanol is a colorless to yellowish liquid with a bitter taste. It is soluble in water and common organic solvents such as ethanol and ether. The compound has a melting point of about 49-52°C and a boiling point of about 305-307°C. It is a chiral compound and exists as optical isomers.

Use:
trans-4-Aminocyclohexanemethanol has a wide range of applications in pharmaceutical synthesis and organic synthesis. It can be used to synthesize many important organic compounds, such as drugs, dyes and functional materials. The importance of this compound lies in its structure, which provides the possibility of introducing amines or other functional groups, thereby providing a flexible platform for the synthesis of compounds.

Method:
The method of preparing trans-4-Aminocyclohexanemethanol generally involves the reduction of cyclohexan-1, 4-dione. One common method of synthesis is reduction using a natural gas catalyst, such as hydrogen and a palladium catalyst. Reaction conditions and specific synthetic routes can be adjusted as needed.

Safety Information:
When using the trans-4-Aminocyclohexanemethanol, you need to pay attention to the following:
1. Appropriate personal protective equipment, such as gloves and glasses, should be worn.
2. Avoid contact with skin and eyes. If contact occurs, rinse immediately with plenty of water.
3. Operate in a well-ventilated place and avoid inhaling gas, steam or mist.
4. Should be stored in a closed container, away from the fire and oxidant.
5. In case of accidental leakage, appropriate measures should be taken to clean up and deal with it.
6. Local regulations and safe practices should be followed when using or disposing of the compound.

Because trans-4-Aminocyclohexanemethanol is a chemical, it needs to be used and stored in a safe environment to ensure the safety of personnel. Before use, it is best to refer to the relevant safety data sheet and accurate chemical practice instructions.

Last Update：2024-04-09 21:32:37