trans-4-(Cbz-aMino)cyclohexan-1-ol - Names and Identifiers
trans-4-(Cbz-aMino)cyclohexan-1-ol - Physico-chemical Properties
Molecular Formula | C14H19NO3
|
Molar Mass | 249.31 |
Density | 1.17±0.1 g/cm3(Predicted) |
Boling Point | 427.6±44.0 °C(Predicted) |
Flash Point | 212.4°C |
Vapor Presure | 4.51E-08mmHg at 25°C |
pKa | 12.15±0.40(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.56 |
trans-4-(Cbz-aMino)cyclohexan-1-ol - Introduction
benzyl (trans-4-hydroxycyclohexyl)carbamate, also known as benzyl (trans-4-hydroxycyclohexyl)carbamate. It is an organic compound with the chemical formula C15H19NO3.
Nature:
benzyl (trans-4-hydroxycyclohexyl)carbamate is a white crystalline solid. It is stable at room temperature and has good solubility in solvents. It is an ester compound with substitution of a benzoyl group (Cbz group) and a hydroxyl group (alcohol group). The high structural stability of this compound makes it widely used in organic synthesis.
Use:
benzyl (trans-4-hydroxycyclohexyl)carbamate is a common intermediate in organic chemical synthesis. It can be used to synthesize compounds containing Cbz-amino groups, such as drugs, pesticides, dyes and photosensitive materials. It can also be used as a temporary protecting group to protect the hydroxyl function.
Method:
benzyl (trans-4-hydroxycyclohexyl)carbamate is mainly prepared by reacting cyclohexanone with the corresponding amine compound (such as benzyl carbamate) under appropriate reaction conditions. This process usually requires a combination of solvent and catalyst to facilitate the reaction.
Safety Information:
benzyl (trans-4-hydroxycyclohexyl)carbamate has low toxicity under normal use conditions. However, as a chemical substance, care should be taken to comply with laboratory safety procedures, avoid contact with skin and eyes, and ensure that the operation is carried out in a well-ventilated environment. If accidental contact or misuse occurs, seek medical help immediately.
Last Update:2024-04-09 15:17:56