trimethyl(prop-1-ynyl)silane
1-(trimethylsilyl)prop-1-yne
CAS: 6224-91-5
Molecular Formula: C6H12Si
trimethyl(prop-1-ynyl)silane - Names and Identifiers
| Name | 1-(trimethylsilyl)prop-1-yne |
| Synonyms | 1-trimethylsilylpropyne 1-(TRIMETYHLSILYL)PROPYNE 1-(Trimethylsilyl)propyne Trimethyl-1-propynylsilane (1-Propynyl)trimethylsilane Trimethyl-prop-1-ynylsilane 1-(Trimethylsilyl)-1-propyne trimethyl(prop-1-ynyl)silane 1-(trimethylsilyl)prop-1-yne Silane, trimethyl-1-propynyl- 1-Methyl-2- triMethylsilylacety trimethyl(prop-1-yn-1-yl)silane |
| CAS | 6224-91-5 |
| EINECS | 228-314-5 |
| InChI | InChI=1/C6H12Si/c1-5-6-7(2,3)4/h1-4H3 |
| InChIKey | DCGLONGLPGISNX-UHFFFAOYSA-N |
trimethyl(prop-1-ynyl)silane - Physico-chemical Properties
| Molecular Formula | C6H12Si |
| Molar Mass | 112.25 |
| Density | 0.758 g/mL at 25 °C (lit.) |
| Melting Point | -69°C |
| Boling Point | 99-100 °C (lit.) |
| Flash Point | 25°F |
| Solubility | Miscible with toluene. |
| Vapor Presure | 43.9mmHg at 25°C |
| Vapor Density | >1 (vs air) |
| Appearance | Liquid |
| Specific Gravity | 0.758 |
| Color | Clear colorless |
| BRN | 1071311 |
| Storage Condition | 2-8°C |
| Sensitive | 4: no reaction with water under neutral conditions |
| Refractive Index | n20/D 1.417(lit.) |
| Physical and Chemical Properties |
trimethyl(prop-1-ynyl)silane - Risk and Safety
| Risk Codes | R11 - Highly Flammable R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection |
| UN IDs | UN 1993 3/PG 2 |
| WGK Germany | 3 |
| TSCA | Yes |
| HS Code | 29319090 |
| Hazard Class | 3 |
| Packing Group | II |
trimethyl(prop-1-ynyl)silane - Reference Information
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| Introduction | 1-(trimethylsilyl) propyne is a colorless liquid, highly substituted indenes can be synthesized via palladium-catalyzed carbocyclic cyclization; Aldehydes are converted to 1, 3-dienes in the presence of Cp2Zr(H)CI, etc. |
| Application | 1-(trimethylsilyl) propyne is a kind of alkynyl silane derivatives, alkynyl silane derivatives is an important pharmaceutical intermediates, is an important silicon-based chemical raw materials, but also important alkynylation reagents, polyalkynes are essential for the preparation of synthetic motifs. There are many applications in Heterocyclic Chemistry, carbon-carbon coupling, pharmaceutical synthesis, catalytic chemistry, and the materials industry. |
| Use | 1-(trimethylsilyl) propyne is an intermediate in organic synthesis and a pharmaceutical intermediate, mainly as a laboratory R & D and chemical medicine synthesis process, mainly through palladium catalyzed carbon cyclization reaction synthesis of highly substituted indenes. highly substituted indenes were synthesized by palladium-catalyzed carbocyclization. 1 Synthesis of indanone by Rhodium-catalyzed reaction with 2-bromophenylboronic acid. |
Last Update：2024-04-10 22:29:15
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