Name | ETOXAZOLE |
Synonyms | yi-5301 etoxazol ETOXAZOLE ETOXAZOLE STANDARD etoxazole (bsi, pa iso) 2-(2,6-Difluorophenyl)-4-... 4-(4-tert-butyl-2-ethoxyphenyl)-2-(2,6-difluorophenyl)-4,5-dihydro-1,3-oxazole Oxazole, 2-(2,6-difluorophenyl)-4-4-(1,1-dimethylethyl)-2-ethoxyphenyl-4,5-dihydro- 2-(2,6-Difluorophenyl)-4-(4-(1,1-dimethylethyl)-2-ethoxyphenyl)-4,5-di hydrooxazole |
CAS | 153233-91-1 |
EINECS | 201-167-4 |
InChI | InChI=1/C21H23F2NO2/c1-5-25-18-11-13(21(2,3)4)9-10-14(18)17-12-26-20(24-17)19-15(22)7-6-8-16(19)23/h6-11,17H,5,12H2,1-4H3 |
InChIKey | IXSZQYVWNJNRAL-UHFFFAOYSA-N |
Molecular Formula | C21H23F2NO2 |
Molar Mass | 359.41 |
Density | 1.15±0.1 g/cm3(Predicted) |
Melting Point | 101-102° |
Boling Point | 449.1±45.0 °C(Predicted) |
Flash Point | 457℃ |
Solubility | Chloroform (Slightly), Methanol (Slightly) |
Vapor Presure | 7.78E-08mmHg at 25°C |
Appearance | neat |
Color | White to Off-White |
BRN | 8930214 |
pKa | 2.04±0.70(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Stability | Hygroscopic |
Refractive Index | 1.537 |
Physical and Chemical Properties | Storage Conditions: 0-6 ℃ |
Hazard Symbols | N - Dangerous for the environment |
Risk Codes | 50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
Safety Description | S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
UN IDs | UN 3077 9 / PGIII |
WGK Germany | 3 |
RTECS | RP6795100 |
Toxicity | LD50 in rats (mg/kg): >5000 orally; >2000 dermally; LC50 (96 hr) in Japanese carp: 0.89 mg/l (Ishida) |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
Introduction | divoxazole is a new type of oxazole special acaricide newly developed by sumitfriends Chemical Co., Ltd. By inhibiting the formation of the embryo of the mite eggs and the molting process from the young mite to the adult mite, the harmful mites are killed, which has the effect of killing and stomach poison, and has no internal absorption, but has strong penetration ability, resistance to rain erosion. Studies have shown that the killing effect of divoxazole on mite eggs and juvenile mites is very strong, and does not kill adult mites, but can significantly inhibit the hatching rate of female adult mites, and can prevent and control the existing acaricides. |
Application | the effect of divoxazole on citrus, cotton, Apple, flowers, vegetables and other crops, whole claw mites, two spotted spider mites, cinnabar mites and other mites have excellent control effect. Its mode of action is to inhibit the formation of the embryo of the mite eggs and the molting process from the young mites to the adult mites. It is effective for the eggs and the young mites, and is ineffective for the adult mites. Therefore, the best control time is the early stage of harm to mites. The drug has strong resistance to rain, and the lasting period is up to 50 days. Use dose is low, register the use of 5000-7500 times the dose of liquid. It is safe to the environment, and has no harm or minimal harm to beneficial insects and mites. |
toxicity | Acute oral LD50>5000mg/kg, acute percutaneous LD50>2000mg/kg, acute inhalation LC50>1.09mg/L; No irritation to rabbit eyes and skin; No sensitization to guinea pig skin; 90D sub-chronic feeding toxicity test in rats maximum non-acting dose: male rats 6.12mg/kg · d, female rats 20.50mg/kg · d; Mutagenicity test: Ames test, mouse bone marrow cell micronucleus chemical test, the results of in vitro chromosome aberration test of mammalian cells were all negative, without mutagenicity; Acute oral LD50>5000mg/kg, acute percutaneous LD50>2000mg/kg, acute oral LD50> 110g/L, acute inhalation LC50>1.09mg/L; Rabbit eyes have mild irritation, rabbit skin irritation; Guinea pig skin sensitization test results for no sensitization. The original drug and 110g/L suspension are low toxicity acaricide. |
toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |