β-Hydroxybutyronitrile
3-Hydroxybutyronitrile
CAS: 4368-06-3
Molecular Formula: C4H7NO
β-Hydroxybutyronitrile - Names and Identifiers
| Name | 3-Hydroxybutyronitrile |
| Synonyms | 3-Hydroxybutanenitrile β-Hydroxybutyronitrile 3-hydroxybutanenitrile 3-HYDROXYBUTYRONITRILE 3-Hydroxybutyronitrile Butanenitrile, 3-hydroxy- beta-Hydroxybutyronitrile 3-Hydroxybutyronitrile, 1-Cyanopropan-2-ol |
| CAS | 4368-06-3 |
| EINECS | 224-457-2 |
| InChI | InChI=1/C4H7NO/c1-4(6)2-3-5/h4,6H,2H2,1H3 |
β-Hydroxybutyronitrile - Physico-chemical Properties
| Molecular Formula | C4H7NO |
| Molar Mass | 85.1 |
| Density | 0.976 g/mL at 25 °C (lit.) |
| Boling Point | 214 °C (lit.) |
| Flash Point | >230°F |
| Vapor Presure | 0.0286mmHg at 25°C |
| pKa | 13.89±0.20(Predicted) |
| Refractive Index | n20/D 1.429(lit.) |
β-Hydroxybutyronitrile - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29269095 |
β-Hydroxybutyronitrile - Introduction
3-Hydroxybutyrronitril (3-Hydroxybutyrronitril) is an organic compound with the chemical formula C4H7NO. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 3-Hydroxybutyronitril is a colorless liquid or solid.
-Melting point: It is in a solid state at room temperature, and the melting point is about 21-24 degrees Celsius.
-Boiling point: about 151 degrees Celsius.
-Solubility: 3-Hydroxybutyrronitril is soluble in water and a variety of organic solvents.
Use:
-Synthetic derivatives: 3-Hydroxybutyronitril can be used as a starting material for the synthesis of various compounds, such as synthetic drugs, pesticides and pigments.
-Polymer preparation: 3-Hydroxybutyronitril can be used as a raw material for polymer synthesis.
Preparation Method:
3-Hydroxybutyronitril can be prepared by the following two methods:
-Pyrrolidine reaction: Acetone is reacted with hydroxylamine to obtain 3-hydroxyacetone, which is then subjected to dehydration and cyanidation to generate 3-Hydroxybutyronitril.
-Cyanide addition reaction: Acetone reacts with sodium cyanide to generate acetone cyanide, and then 3-Hydroxybutyronitril is obtained through alkali-catalyzed addition reaction.
Safety Information:
- 3-Hydroxybutyronitril is potentially dangerous and care should be taken to avoid contact with skin, eyes and inhalation.
-Appropriate protective equipment, such as gloves, goggles and protective clothing, must be worn when using or handling 3-Hydroxybutyrronitril.
-When storing and handling 3-Hydroxybutyronitril, appropriate safety measures should be taken to prevent leakage and fire.
-If ingested or inhaled, seek medical attention immediately. In case of skin or eye contact, rinse immediately with plenty of water for 15 minutes and seek medical examination.
-When using 3-Hydroxybutyrronitril, please carefully read and understand its safety data sheet (SDS) and follow relevant safety operating procedures.
Nature:
-Appearance: 3-Hydroxybutyronitril is a colorless liquid or solid.
-Melting point: It is in a solid state at room temperature, and the melting point is about 21-24 degrees Celsius.
-Boiling point: about 151 degrees Celsius.
-Solubility: 3-Hydroxybutyrronitril is soluble in water and a variety of organic solvents.
Use:
-Synthetic derivatives: 3-Hydroxybutyronitril can be used as a starting material for the synthesis of various compounds, such as synthetic drugs, pesticides and pigments.
-Polymer preparation: 3-Hydroxybutyronitril can be used as a raw material for polymer synthesis.
Preparation Method:
3-Hydroxybutyronitril can be prepared by the following two methods:
-Pyrrolidine reaction: Acetone is reacted with hydroxylamine to obtain 3-hydroxyacetone, which is then subjected to dehydration and cyanidation to generate 3-Hydroxybutyronitril.
-Cyanide addition reaction: Acetone reacts with sodium cyanide to generate acetone cyanide, and then 3-Hydroxybutyronitril is obtained through alkali-catalyzed addition reaction.
Safety Information:
- 3-Hydroxybutyronitril is potentially dangerous and care should be taken to avoid contact with skin, eyes and inhalation.
-Appropriate protective equipment, such as gloves, goggles and protective clothing, must be worn when using or handling 3-Hydroxybutyrronitril.
-When storing and handling 3-Hydroxybutyronitril, appropriate safety measures should be taken to prevent leakage and fire.
-If ingested or inhaled, seek medical attention immediately. In case of skin or eye contact, rinse immediately with plenty of water for 15 minutes and seek medical examination.
-When using 3-Hydroxybutyrronitril, please carefully read and understand its safety data sheet (SDS) and follow relevant safety operating procedures.
Last Update：2024-04-09 02:00:46
