三乙酰阿扎胞苷
2',3',5'-Triacetyl -azacytidine
CAS: 10302-78-0
Molecular Formula: C14H18N4O8
三乙酰阿扎胞苷 - Names and Identifiers
| Name | 2',3',5'-Triacetyl -azacytidine |
| Synonyms | Nsc291930 Intermediate of Azacitidine 2',3',5'-Triacetyl -azacytidine 2',3',5'-triacetyl-5-Azacytidine 2',3',5'-triacetyl-5-Azacytosine 2'',3'',5''-Triacetyl -Azacytidine 2'',3'',5''-Triacetyl -azacytidine 4-amino-1-(2,3,5-tri-O-acetylpentofuranosyl)-1,3,5-triazin-2(1H)-one 1,3,5-Triazin-2(1H)-one, 4-amino-1-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)- S-Triazin-2(1H)-one, 4-amino-1-.beta.-D-ribofuranosyl-, triacetate (ester) 1,3,5-Triazin-2(1H)-one, 4-aMino-1-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)- 1,3,5-Triazin-2(1H)-one, 4-amino-1-(2,3,5-tri-o-acetyl-.beta.-D-ribofuranosyl)- (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate |
| CAS | 10302-78-0 |
| InChI | InChI=1/C14H18N4O8/c1-6(19)23-4-9-10(24-7(2)20)11(25-8(3)21)12(26-9)18-5-16-13(15)17-14(18)22/h5,9-12H,4H2,1-3H3,(H2,15,17,22) |
三乙酰阿扎胞苷 - Physico-chemical Properties
| Molecular Formula | C14H18N4O8 |
| Molar Mass | 370.31 |
| Density | 1.60±0.1 g/cm3(Predicted) |
| Boling Point | 497.3±55.0 °C(Predicted) |
| Flash Point | 254.6°C |
| Vapor Presure | 5E-10mmHg at 25°C |
| pKa | 3.06±0.20(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
| Refractive Index | 1.633 |
| Physical and Chemical Properties | Storage Conditions: Store at 0-5 ℃ |
三乙酰阿扎胞苷 - Introduction
Triacetyl -5-, also known as 3-acetylamino-5-aza-1-Δ4-piperidinone nucleoside (azacytidine nucleoside), is a nucleoside compound. The following is a description of its nature, use, formulation and safety information:
Nature:
Triacetyl-5-azacytidine is a white crystalline solid that is stable at ambient temperature. It has a strong polarity, soluble in water and organic solvents. Its chemical structure contains nitrogen and amide functional groups, which make it have special chemical and biological activities.
Use:
Triacetyl -5-azacytidine is mainly used as a pharmaceutical intermediate and research reagent. In the field of medicine, it is used to synthesize antiviral drugs, such as anti-HIV drugs. In the field of scientific research, it is often used to synthesize biologically active molecules or heterocyclic compounds. In addition, it can also be used for DNA synthesis and virus suppression.
Preparation Method:
Triacetyl -5-azacytidine is generally obtained by chemical synthesis. Common methods of preparation include synthesis of nucleotides and chemical modification of functional groups. The specific preparation method can be selected according to the desired purity and scale.
Safety Information:
Triacetyl-5-azacytidine is less toxic and dangerous, but it is still a chemical substance that needs to be handled correctly in the laboratory. When handling, take appropriate protective measures, such as wearing gloves and protective glasses, to avoid inhalation or contact with the skin. If ingested by mistake or into the eyes or skin, rinse immediately with plenty of water and seek medical help. In addition, the compound should be stored in a dry, cool, well-ventilated place, away from fire sources and flammable materials. During use and storage, be sure to carefully read and follow the relevant safety data sheets and instructions for use.
Nature:
Triacetyl-5-azacytidine is a white crystalline solid that is stable at ambient temperature. It has a strong polarity, soluble in water and organic solvents. Its chemical structure contains nitrogen and amide functional groups, which make it have special chemical and biological activities.
Use:
Triacetyl -5-azacytidine is mainly used as a pharmaceutical intermediate and research reagent. In the field of medicine, it is used to synthesize antiviral drugs, such as anti-HIV drugs. In the field of scientific research, it is often used to synthesize biologically active molecules or heterocyclic compounds. In addition, it can also be used for DNA synthesis and virus suppression.
Preparation Method:
Triacetyl -5-azacytidine is generally obtained by chemical synthesis. Common methods of preparation include synthesis of nucleotides and chemical modification of functional groups. The specific preparation method can be selected according to the desired purity and scale.
Safety Information:
Triacetyl-5-azacytidine is less toxic and dangerous, but it is still a chemical substance that needs to be handled correctly in the laboratory. When handling, take appropriate protective measures, such as wearing gloves and protective glasses, to avoid inhalation or contact with the skin. If ingested by mistake or into the eyes or skin, rinse immediately with plenty of water and seek medical help. In addition, the compound should be stored in a dry, cool, well-ventilated place, away from fire sources and flammable materials. During use and storage, be sure to carefully read and follow the relevant safety data sheets and instructions for use.
Last Update：2024-04-09 20:52:54
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Product Name: 2'',3'',5''-Triacetyl -azacytidine Visit Supplier Webpage Request for quotation
CAS: 10302-78-0
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CAS: 10302-78-0
Tel: 18301782025
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