克立硼罗杂质64 - Names and Identifiers
Name | Benzonitrile, 4-[3-[(acetyloxy)methyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborola
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Synonyms | Crisaborole-007 Crisaborole Impurity 64 Benzonitrile, 4-[3-[(acetyloxy)methyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborola Benzonitrile, 4-[3-[(acetyloxy)methyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]-
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CAS | 2227126-13-6
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克立硼罗杂质64 - Physico-chemical Properties
Molecular Formula | C22H24BNO5
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Molar Mass | 393.24 |
Density | 1.18±0.1 g/cm3(Predicted) |
Boling Point | 516.3±50.0 °C(Predicted) |
克立硼罗杂质64 - Introduction
Benzonitril, 4-[3-[(acetyloxy)methyl]-4-(4,4, 5,5-tetrathyl-1, 3,2-dioxaborola, also known as Benzonitrile, 4-[3-[(acetyloxy)methyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborola), is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
- Benzonitrile, 4-[3-[(acetyloxy)methyl]-4-(4,4, 5,5-tetrathyl-1, 3,2-dioxaborola is a colorless to pale yellow liquid with a strong odor.
-Its molecular formula is C13H19BO5 and its molecular weight is 278.10g/mol.
-The compound is insoluble in water at room temperature, but can be dissolved in organic solvents such as methanol, ethanol and Ether solvents.
Use:
-benzonitril, 4-[3-[(acetyloxy)methyl]-4-(4,4, 5,5-tetrathyl-1, 3,2-dioxaborola is widely used in the pharmaceutical field. It can be used as intermediates or reagents for the synthesis of various drugs and pharmaceutical compounds.
-It is often used in the etherification and dehydration of alcohols in organic synthesis reactions.
-The compound can also be used as a precursor for dyes and pigments.
Method:
- Benzonitrile, 4-[3-[(acetyloxy)methyl]-4-(4,4, 5,5-tetrathyl-1, 3,2-dioxaborola is usually obtained by chemical synthesis in the laboratory. A commonly used synthesis method is to combine an appropriate amount of 4-[3-[(acetyloxy)methyl]-4-(4,4, 5,5-tetrathyl-1, 3,2-dioxaborola) the Benzonitrile is reacted with an appropriate amount of sodium hydroxide in an organic solvent.
-In industrial production, the compound is usually synthesized through a multi-step reaction, and the specific method varies from manufacturer to manufacturer.
Safety Information:
- Benzonitrile, 4-[3-[(acetyloxy)methyl]-4-(4,4, 5,5-tetrathyl-1, 3,2-dioxaborola is generally safe under normal use conditions, but individual differences and possible risks still need to be paid attention.
-Avoid contact with skin and eyes when using, and wear protective gloves and goggles when necessary.
-If ingestion or exposure to a large amount, please seek medical help immediately and bring the safety data sheet of the compound to the doctor to explain the situation.
Last Update:2024-04-09 15:18:03