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化合物BOC-VAL-CIT-PAB

Boc-Val-Cit-PABA

CAS: 870487-09-5

Molecular Formula: C23H37N5O6

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化合物BOC-VAL-CIT-PAB - Names and Identifiers

Name Boc-Val-Cit-PABA
Synonyms Boc-Val-Cit-PABA
Boc-Val-Cit-PAB-OH
Boc-Gly-Gly-Phe-Gly
Pentanoicacid,2,6-dioxo-,methylester
(S)-2-[(S)-2-(Boc-amino)-3-methylbutanamido]-N-[4-(hydroxymethyl)phenyl]-5-ureidopentanamide
N-[(1,1-Dimethylethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide
L-Ornithinamide, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-
tert-butyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate
CAS 870487-09-5

化合物BOC-VAL-CIT-PAB - Physico-chemical Properties

Molecular FormulaC23H37N5O6
Molar Mass479.57
Density1.209±0.06 g/cm3(Predicted)
Boling Point771.3±60.0 °C(Predicted)
pKa11.25±0.46(Predicted)
Storage Condition2-8°C
Physical and Chemical PropertiesBioactive Boc-Val-Cit-PAB is a degradable (cleavable) ADC linker that can be used to synthesize antibody-coupled drugs (ADC).
UseThe Boc-Val-Cit-PAB of use is a cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs).
In vitro study ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
In vivo studyThe ADC is composed of an antibody, and the ADC cytotoxin is bound to the antibody via the ADC linker.

化合物BOC-VAL-CIT-PAB - Preparation solution concentration reference

 1mg5mg10mg
1 mM2.085 ml10.426 ml20.852 ml
5 mM0.417 ml2.085 ml4.17 ml
10 mM0.209 ml1.043 ml2.085 ml
5 mM0.042 ml0.209 ml0.417 ml
Last Update:2024-01-02 23:10:35

化合物BOC-VAL-CIT-PAB - Uses and synthesis methods

In vivo studies

ADC is composed of antibodies, which bind ADC cytotoxins to antibodies through ADC connectors.

Target

Cleavable

in vitro studies

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Last Update:2024-04-09 01:59:50

化合物BOC-VAL-CIT-PAB - Reference Information

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
use Boc-Val-Cit-PAB are cleavable ADC connectors for the synthesis of antibody-drug conjugates (ADC).
in vivo study ADC consists of antibodies, which bind ADC cytotoxins to antibodies through ADC connectors.
biological activity Boc-Val-Cit-PAB is a degradable (cleavable) ADC linker that can be used to synthesize antibody-coupled drugs (ADC).
target Cleavable
in vitro study
Last Update:2024-04-09 01:59:58
化合物BOC-VAL-CIT-PAB
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MedChemExpress (MCE)
Spot supply
Product Name: Boc-Val-Cit-PAB Visit Supplier Webpage Request for quotation
CAS: 870487-09-5
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Boc-Val-Cit-PABA Visit Supplier Webpage Request for quotation
CAS: 870487-09-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: Boc-Val-Cit-PABA Visit Supplier Webpage Request for quotation
CAS: 870487-09-5
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: Boc-Val-Cit-PABA;Boc-Val-Cit-PAB Visit Supplier Webpage Request for quotation
CAS: 870487-09-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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化合物BOC-VAL-CIT-PAB
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