叔丁基12-氨基-4,7,10-三氮杂十一烷酸酯
tert-Butyl 12-amino-4,7,10-trioxadodecanoate
CAS: 252881-74-6
Molecular Formula: C13H27NO5
叔丁基12-氨基-4,7,10-三氮杂十一烷酸酯 - Names and Identifiers
叔丁基12-氨基-4,7,10-三氮杂十一烷酸酯 - Physico-chemical Properties
| Molecular Formula | C13H27NO5 |
| Molar Mass | 277.36 |
| Density | 1.029±0.06 g/cm3(Predicted) |
| Boling Point | 358.5±27.0 °C(Predicted) |
| Flash Point | 169.7°C |
| pKa | 8.74±0.10(Predicted) |
| Storage Condition | -20°C |
| MDL | MFCD06201017 |
| Use | Intermediate in the spacer arm used in synthetic combinatorial chemistry |
叔丁基12-氨基-4,7,10-三氮杂十一烷酸酯 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-34 |
叔丁基12-氨基-4,7,10-三氮杂十一烷酸酯 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.605 ml | 18.027 ml | 36.054 ml |
| 5 mM | 0.721 ml | 3.605 ml | 7.211 ml |
| 10 mM | 0.361 ml | 1.803 ml | 3.605 ml |
| 5 mM | 0.072 ml | 0.361 ml | 0.721 ml |
Last Update：2024-01-02 23:10:35
叔丁基12-氨基-4,7,10-三氮杂十一烷酸酯 - Reference Information
| overview | polyethylene glycol (Polyethyleneglycol,PEG) is formed by ring-opening polymerization of ethylene oxide, and the ratio of oxygen element to carbon element in its molecular formula is as high as 1:2. This unique structure gives it excellent water solubility and biocompatibility. Coupling polyethylene glycol to the surface of polypeptide or protein drugs can increase the water solubility of the drug, prolong the half-life of the drug, and reduce the immunogenicity of the drug. In addition, polyethylene glycol has low toxicity and can be excreted by the kidneys without accumulating in the body. |
| use | 12-amino -4,7,10-tert-butyl trioxododecanoate can be used as an intermediate in pharmaceutical synthesis, such as preparing amino polyethylene glycol propionic acid. |
Last Update：2024-04-10 22:29:15
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View History
叔丁基12-氨基-4,7,10-三氮杂十一烷酸酯
3,7-二甲基辛酸-2,6-二烯酸
Bismuth trioxide
氯鄰苯二甲酸
4-AMINOPIPERIDINE, 1-BOC PROTECTED
伏格列波糖中间体
2-Methyl-2-[4-(4-chlorobenzyl)phenoxy]propionic acid isopropyl ester
NSC 62530
ISOBUTYL ALPHA-TOLUATE
3-(4-(6-METHYLBENZO[D]THIAZOL-2-YL)PHENYLAMINO)-5-P-TOLYLCYCLOHEX-2-ENONE
3,7-二甲基辛酸-2,6-二烯酸
Bismuth trioxide
氯鄰苯二甲酸
4-AMINOPIPERIDINE, 1-BOC PROTECTED
伏格列波糖中间体
2-Methyl-2-[4-(4-chlorobenzyl)phenoxy]propionic acid isopropyl ester
NSC 62530
ISOBUTYL ALPHA-TOLUATE
3-(4-(6-METHYLBENZO[D]THIAZOL-2-YL)PHENYLAMINO)-5-P-TOLYLCYCLOHEX-2-ENONE