告达庭 - Names and Identifiers
Name | Caudatin
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Synonyms | caudatin Caudatin Pregn-5-en-20-one,12-[[(2E)-3,4-dimethyl-1-oxo-2-pentenyl]oxy]-3,8,14,17-tetrahydroxy-, (3b,12b,14b,17a)- Pregn-5-en-20-one, 12-[[(2E)-3,4-dimethyl-1-oxo-2-pentenyl]oxy]-3,8,14,17-tetrahydroxy-, (3β,12β,14β,17α)- (3beta,12beta,14beta,17alpha)-12-[[(2E)-3,4-Dimethyl-1-oxo-2-pentenyl]oxy]-3,8,14,17-tetrahydroxypregn-5-en-20-one [(3S,8S,9R,10R,12R,13S,14R,17R)-17-acetyl-3,8,14,17-tetrahydroxy-10,13-dimethyl-1,2,3,4,7,9,11,12,15,16-decahydrocyclopenta[a]phenanthren-12-yl] (E)-3,4-dimethylpent-2-enoate
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CAS | 38395-02-7
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告达庭 - Physico-chemical Properties
Molecular Formula | C28H42O7
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Molar Mass | 490.63 |
Density | 1.25 |
Melting Point | 158-160°C |
Boling Point | 617.9±55.0 °C(Predicted) |
Specific Rotation(α) | (c, 0.5 in CHCl3)+20.8 |
Solubility | Soluble in ethyl acetate, acetone, DMSO and other organic solvents. |
Appearance | White powder |
pKa | 11.93±0.70(Predicted) |
Storage Condition | 2-8℃ |
MDL | MFCD09752778 |
Physical and Chemical Properties | White crystalline powder, soluble in organic solvents such as methanol, ethanol, DMSO, etc., is derived from the yellow wattle, the Lomoceae plant. |
告达庭 - Reference
Reference Show more | 1. Xu Huiqing, Feng Jin, Li Chunyang, et al. Optimization of thermal reflux extraction of C21 steroidal glycosides from Cynanchum auriculatum by response surface methodology [J]. Journal of Southern agriculture, 2019 050(006):P.1304-1311. 2. Sun Wanjin, Jin Shi, Bai Shushen, etc. Study on HPLC fingerprint of Xiaozhong Ⅰ ointment [J]. West China Pharmaceutical Journal, 2019, v.34(06):72-75. 3. [IF = 4.759] Xu Wang et al."A rapid and practical prediction method for the Arizona nonlinear system family used in high speed countercurrent chromatography." J Chromatogr A. 2020 Oct;1629:461426 |
告达庭 - Introduction
Caudatin (also known as Trichosanthes kirilowii) is a natural product, mainly found in Chinese herbal medicine Trichosanthes. The following is a description of the nature, use, formulation and safety information of Caudatin:
Nature:
Caudatin is a white crystalline powder, odorless, slightly soluble in water, soluble in alcohol solvents. It has antioxidant, anti-inflammatory, anti-tumor and antibacterial activities.
Use:
Caudatin has a variety of pharmacological effects and medical application value. It is widely used in the field of traditional Chinese medicine for the treatment of rheumatism, blood stasis syndrome, rheumatoid arthritis and other diseases. In addition, Caudatin also shows potential anticancer activity and has some potential in tumor therapy. It can also be used in areas such as synthetic drugs and cosmetics.
Preparation Method:
The preparation method of Caudatin is mainly obtained by extracting from Trichosanthes kirilowinaceae plants. The general preparation method is to crush the dried plant material, then extract it with a solvent (such as ethanol, water, etc.), and obtain pure Caudatin through process steps such as distillation and crystallization.
Safety Information:
Regarding the safety of Caudatin, further research is needed to ensure its safe use. As a natural product, Caudatin is considered safe to some extent. However, attention should still be paid to proper dosage and usage during use. Especially for pregnant women, lactating women, as well as children and the elderly, should follow the doctor's advice. In addition, if any discomfort or allergic reaction occurs, you should immediately discontinue use and consult a doctor. Before using Caudatin, consult a professional physician for more detailed and personalized safety information.
Last Update:2024-04-09 21:54:55