大黄酚-8-O-葡萄糖苷

大黄酚-8-O-葡萄糖苷 - Names and Identifiers

Name	Chrysophanol-8-O-β-D-glucopyranoside
Synonyms	Chrysophanol-8-glucoside Chrysophal 8-O-glucoside Chrysophanol 8-O-glucoside Chrysophanol-8-O-β-D- glucoside chrysophanol 8-O-beta-D-glucoside Chrysophanol-8-O-β-D-glucopyranoside Chrysophanol-8-O-beta-D-glucopyranoside 9,10-Anthracenedione, 8-(β-D-glucopyranosyloxy)-1-hydroxy-3-methyl-
CAS	13241-28-6

大黄酚-8-O-葡萄糖苷 - Physico-chemical Properties

Molecular Formula	C21H20O9
Molar Mass	416.38
Density	1.596±0.06 g/cm3(Predicted)
Melting Point	110 °C
Boling Point	763.2±60.0 °C(Predicted)
Solubility	Soluble in methanol, ethanol, DMSO and other organic solvents.
Appearance	Yellow powder
pKa	6.82±0.20(Predicted)
Storage Condition	2-8℃
MDL	MFCD20260508
Physical and Chemical Properties	Pale yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the dry root and rhizome of the Polygonaceae plant palm leaf rhubarb.

大黄酚-8-O-葡萄糖苷 - Reference

Reference

1. Sun Yunbo, Shen Shuo, Zhang Chuanfeng et al. Study on HPLC fingerprint of Rhodiola rosea in hongba township, Sichuan [J]. China Medical leads 2020v.17;No.534(04):29-33.
2. Lin, Longfei, et al. "Hepathotoxicity and mechanism study of chrysophanol-8-O-glucoside in vitro." Biomedicine & Pharmacotherapy 120 (2019): 109531.https://doi.org/10.1016/j.biopha.2019.109531
3. [IF = 2.896] Longfei Lin et al. "The Simultaneous determination and pharmacokinetic study of P-hydroxybenzaldehyde, 2,3,5,4, and emodin in rat plasma by liquid chromatography tandem mass spectrometry aft
4. [IF=3.743] Longfei Lin et al."Hepatotoxicity and mechanism study of chrysophanol-8-O-glucoside in vitro."Biomed Pharmacother. 2019 Dec;120:109531

大黄酚-8-O-葡萄糖苷 - Introduction

It is a plant compound also known as emodin-8-o-glucoside. Its chemical structure includes two parts: chrysophanol and glucoside.

Regarding the nature of the crystal, it is a yellow crystalline powder that can be dissolved in water. It has a bitter taste and is more stable under acidic conditions than under neutral or alkaline conditions. Its chemical properties make it a relatively stable natural pigment.

It is widely used in food, health care products and cosmetics. It can be used as a food additive and natural pigment to give food a yellow or orange color. In addition, it also has certain antioxidant properties and can be used for the addition of antioxidants.

The preparation of phenol is generally obtained by esterification reaction with glucose after extraction from plants containing chrysophanol. The extraction and purification process requires certain chemical techniques.

Regarding safety information, it is currently considered a relatively safe and non-toxic substance. However, for certain groups of people, such as people with allergies or the presence of a particular disease, it may trigger an allergic reaction or discomfort. In the process of use, the corresponding dosage and use regulations should be followed to ensure the safety of use. For uses such as food additives and cosmetics, it is often necessary to follow relevant regulations and standards. Before use, it is recommended to consult relevant professionals or institutions to ensure correct and safe use.

Last Update：2024-04-09 21:54:55

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