奥洛他定中间体II

奥洛他定中间体II - Names and Identifiers

Name	(3-dimethylaminopropyl)triphenylphospho-nium bromo hydrobromide
Synonyms	[3-(Dimethylamino)pr triphenylphosphoniuM broMide hydrobroMide [3-(DiMethylaMino)propyl]triphenylphosphoniuM broM 3-dimethylaminopropyltriphenylphosphonium bromide HBr (3-DIMETHYLAMINOPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE HBR [3-(dimethylammonio)propyl](triphenyl)phosphonium dibromide [3-(Dimethylamino)propyl] Triphenyl Phosphonium Bromide HBr (3-dimethylaminopropyl)triphenylphospho-nium bromo hydrobromide (3-diMethylaMinopropyl)triphenylphospho-niuM broMo hydrobroMide (3-Dimethylaminopropyl)triphenylphosphonium bromide hydrobromide (3-DIMETHYLAMINOPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE HYDROBROMIDE [3-(dimethylamino)propyl]triphenylphosphonium bromide hydrobromide Phosphonium,[3-(dimethylamino)propyl]triphenyl bromide hydrobromide Phosphonium [3-(dimethylamino)propyl]triphenyl bromide hydrobromide (3-(DiMethylaMino)propyl)triphenylphosphoniuM broMide hydrobroMidepuruM
CAS	27710-82-3
EINECS	608-135-2
InChI	InChI=1/C23H27NP.2BrH/c1-24(2)19-12-20-25(21-13-6-3-7-14-21,22-15-8-4-9-16-22)23-17-10-5-11-18-23;;/h3-11,13-18H,12,19-20H2,1-2H3;2*1H/q+1;;/p-1

奥洛他定中间体II - Physico-chemical Properties

Molecular Formula	C23H28Br2NP
Molar Mass	509.27
Melting Point	283-285°C
Solubility	Chloroform (Slightly), Methanol (Slightly)
Appearance	Solid
Color	Off-White
Storage Condition	Inert atmosphere,Room Temperature
Stability	Hygroscopic

奥洛他定中间体II - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
FLUKA BRAND F CODES	3-10

奥洛他定中间体II - Introduction

(3-dimethylaminoppyl) triphenylphospho-nium bromo hydrobromide is an organophosphorus compound. The following are the properties, use, preparation and safety information of the compound:

Nature:
-Appearance: White crystalline powder
-Solubility: Soluble in organic solvents, insoluble in water
-Melting point: About 180-185 degrees Celsius
-Chemical properties: The compound has phosphorus ion and triphenylmethane cation, which can be used as a nucleophile of bromide ion to participate in the reaction.

Use:
-This compound is often used as a catalyst or catalyst precursor in organic synthesis reactions, especially in phosphorus activation reactions.
-It can also be used to synthesize organophosphorus complexes or organometallic complexes.

Method:
(3-dimethylaminoppyl) triphenylphospho-nium bromo hydrobromide is generally synthesized by the following steps:
1. First, 3-dimethylaminopropanol is reacted with bromopropane to generate 3-(dimethylamino) propyl bromide.
2. Next, 3-(dimethylamino) propyl bromide is reacted with triphenylphosphine to produce [3-(dimethylamino) propyl] triphenylphosphonium bromide.
3. Finally, [3-(dimethylamino) propyl] triphenylphosphonium bromide is reacted with hydrobromic acid to generate (3-dimethylaminopropyl)triphenylphospho-nium bromo hydrobromide.

Safety Information:
-This compound is an organophosphorus compound with certain toxicity and requires appropriate safety measures during operation, such as wearing gloves, goggles and protective clothing.
-Because it is an organophosphorus compound, it may exhibit neurotoxicity and irritation, so it should be kept away from fire and high temperature.
-When using or handling, follow relevant safety procedures and store the compound properly.

Last Update：2024-04-09 21:04:16