帕洛诺司琼相关化合物A

帕洛诺司琼相关化合物A - Names and Identifiers

Name	(3aS)-2-[(3S)-1-oxidoquinuclidin-1-ium-3-yl]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one
Synonyms	LogP Palonosetron N-Oxide Palosetron nitrogen oxides Palonosetron USP Related Compound A PALONOSETRON USP RELATED COMPOUND A (PALONOSETRON N-OXIDE) (S)-3-((S)-1-oxo-3a,4,5,6-tetrahydro-1H-benzo[de]isoquinolin-2(3H)-yl)quinuclidine 1-oxide (3aS)-2-[(3S)-1-oxidoquinuclidin-1-ium-3-yl]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one (3aS)-2,3,3a,4,5,6-Hexahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-1H-benz[de]isoquinolin-1-one 1H-Benz[de]isoquinolin-1-one,2,3,3a,4,5,6-hexahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-,(3aS)-
CAS	813425-83-1
InChI	InChI=1/C19H24N2O2/c22-19-16-6-2-4-14-3-1-5-15(18(14)16)11-20(19)17-12-21(23)9-7-13(17)8-10-21/h2,4,6,13,15,17H,1,3,5,7-12H2/t13?,15-,17-,21?/m1/s1

帕洛诺司琼相关化合物A - Physico-chemical Properties

Molecular Formula	C19H24N2O2
Molar Mass	312.41
Melting Point	62 - 65°C
Solubility	Dichloromethane (Slightly), Methanol (Slightly)
Appearance	Solid
Color	Light Yellow to Beige
pKa	4.72±0.40(Predicted)
Storage Condition	Hygroscopic, -20°C Freezer, Under Inert Atmosphere

帕洛诺司琼相关化合物A - Risk and Safety

HS Code

29339900

帕洛诺司琼相关化合物A - Introduction

(3aS)-[(3S)-2-]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one is an organic compound with the chemical formula C19H19N2O2. The following is an introduction to some of its properties, uses, methods and safety information:

Properties:(3aS)-2-[(3S)-Ti]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one is a solid with a white to light yellow color. It is an organic cationic compound with a structure similar to a quaternary ammonium salt. Its melting point is 160-165 degrees Celsius.

usage:(3aS)-2-[(3S)-Ti]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one is a drug intermediate, commonly used in the synthesis of drugs and other organic compounds. It has a wide range of applications in the pharmaceutical field, such as as sedatives, antiepileptic drugs and antidepressants.

preparation method:(3aS)-2-[(3S)-Ti]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one is prepared by various methods, and the common method is obtained by reacting palonosetron with an oxidizing agent. The specific method will involve a series of chemical steps and the formation of intermediates, which need to be carried out under suitable experimental conditions.

safety information: because (3aS)-2-[(3S)-]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one is an organic compound, it is necessary to pay attention to safety and comply with corresponding laboratory safety rules and regulations when using and handling. It can be irritating and toxic to humans, so direct contact with skin, eyes and inhalation of its dust or vapours should be avoided. Wear protective glasses, gloves and protective masks during operation. In addition, the proper storage and disposal of waste is also very important.

Last Update：2024-04-09 20:52:54