替卡格雷洛杂质E - Names and Identifiers
Name | (1S,2S,3R,5S)-3-((3-((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)- 5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-5- (2-hydroxyethoxy)cyc
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Synonyms | Ticagrelor-5 Tigrelo Impurity E Ticagrelor Sulphone Ticagrelor Triazole Isomer Ticagrelor Related Compound 41 (1S,2S,3R,5S)-3-((3-((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)- 5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-5- (2-hydroxyethoxy)cyc (1S,2S,3R,5S)-3-((3-((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol N-((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)-N-(3-((1R,2S,3S,4S)-2,3-dihydroxy-4-(2-hydroxyethoxy)cyclopentyl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)nitrous amide
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CAS | 1788033-05-5
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替卡格雷洛杂质E - Physico-chemical Properties
Molecular Formula | C23H28F2N6O4S
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Molar Mass | 522.57 |
Density | 1.67±0.1 g/cm3(Predicted) |
Boling Point | 777.6±70.0 °C(Predicted) |
pKa | 13?+-.0.70(Predicted) |
Storage Condition | -20℃ |
替卡格雷洛杂质E - Introduction
(1S,2S,3R,5S)-3-((3-((1R,2S)-2-(3,4-difluorophenyl) cyclopyl) -5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-5- (2-hydroxyethoxy)cyc(Tegaserod Impurity E) is an Impurity of ticagrelor, its chemical name is (1S,2S,3R,5S)-3-((3-((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)) -5-(Propylthio)-3H-[1,2,3] triazole [4,5-d]pyrimidin-7-yl)amino)-5- (2-hydroxyethoxy) ring. The following is a description of its nature, use, preparation and safety information:
Nature:
(1S,2S,3R,5S)-3-((3-((1R,2S)-2-(3,4-difluorophenyl) cyclopyl)) -5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-5- (2-hydroxyethoxy)cyc is an organic compound, it has a solid form. It is stable at room temperature and can be stored under appropriate conditions.
Use:
(1S,2S,3R,5S)-3-((3-((1R,2S)-2-(3,4-difluorophenyl) cyclopyl)) -5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-5- (2-hydroxyethoxy)cyc is commonly used as a reference standard for related substances for ticagrelor drugs or for quality control purposes. It can be used to determine the purity and quality of drugs, and can be used for related analytical tests in drug research.
Method:
(1S,2S,3R,5S)-3-((3-((1R,2S)-2-(3,4-difluorophenyl) cyclopyl)) -5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-5- (2-hydroxyethoxy) the preparation of cyc can be carried out by synthetic chemical methods. Specific synthetic routes are developed and optimized according to actual needs and requirements.
Safety Information:
Since (1S,2S,3R,5S)-3-((3-((1R,2S)-2-(3,4-difluorophenyl) cyclopyl)) -5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-5- (2-hydroxyethoxy)cyc is an impurity of the ticagrelor drug, and the relevant safety information and toxicity data may be similar to that of ticagrelor itself. Use and processing of (1S,2S,3R,5S)-3-((3-((1R,2S)-2-(3,4-difluorophenyl) cyclopyl) -5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-5- (2-hydroxyethoxy)cyc should follow the relevant safety operation guidelines and laboratory rules and regulations to ensure the safety of personnel and the reliability of the experiment.
It should be noted that the above information is for reference only, and should be evaluated and confirmed according to the specific situation and relevant regulatory requirements in actual use. It is best to consult relevant professional bodies or experts before using any chemical substance.
Last Update:2024-04-09 21:32:49