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替诺福韦艾拉酚胺富马酸半盐

Tenofovir Alafenamide fumarate

CAS: 1392275-56-7

Molecular Formula: C25H33N6O9P

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替诺福韦艾拉酚胺富马酸半盐 - Names and Identifiers

Name Tenofovir Alafenamide fumarate
Synonyms Anti-HIV
GS-7340 (hemifumarate)
Tenofovir Alafenamide fumarate
Tenofovir levamide amine fumarate
GS7340(Tenofovir Alafenamide Fumarate)
TENOFOVIR ALAFENAMIDE HEMIFUMARATE (GS-7340 HEMIFUMARATE)
CAS 1392275-56-7
EINECS 805-448-8

替诺福韦艾拉酚胺富马酸半盐 - Physico-chemical Properties

Molecular FormulaC25H33N6O9P
Molar Mass592.55
Solubility DMSO
Storage ConditionKeep in dark place,Sealed in dry,Room Temperature
UseThis product is for scientific research only and shall not be used for other purposes.
In vitro study Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) antiviral activities are similar across all cell types, ranging from 5 to 7 nM, while the CC 50 varies from 4.7 to 42 μM for MT-4 and MT-2 cells, respectively. The antiviral activity of TAF is evaluated against a panel of HIV-1 and HIV-2 isolates, including HIV-1 group M subtypes A to G, as well as group N and O isolates. Overall, for the 29 primary HIV-1 isolates tested in PBMCs, TAF EC 50 s range from 0.1 to 12 nM, with a mean EC 50 of 3.5 nM compared to a mean EC 50 of 11.8 nM for AZT, which is used as an internal control. For the HIV-2 isolates, the mean EC 50 s are 1.8 nM for TAF and 6.4 nM for AZT.
In vivo study Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an amidate prodrug of Tenofovir with good oral bioavailability and increases plasma stability compared to Tenofovir disoproxil fumarate (TDF) .
替诺福韦艾拉酚胺富马酸半盐
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Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: Tenofovir Alafenamide fumarate Request for quotation
CAS: 1392275-56-7
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CHEMBSF (Shanghai) Biomedical Technology Co., Ltd
Spot supply
Product Name: Tenofovir Alafenamide fumarate Request for quotation
CAS: 1392275-56-7
Tel: +86-18721521379
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Nantong Reform Petro-Chemical CO., LTD.
Spot supply
Product Name: Tenofovir Alafenamide fumarate Request for quotation
CAS: 1392275-56-7
Tel: +86-17551318830
Email: r@reformchem.com­
Mobile: +86-17551318830
QQ: 3785839865 Click to send a QQ messageSend QQ message
Wechat: chemical6666 
MedChemExpress (MCE)
Multiple SpecificationsSpot supply
Product Name: Tenofovir alafenamide hemifumarate Visit Supplier Webpage Request for quotation
CAS: 1392275-56-7
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: Tenofovir alafenamide hemifumarate H210-F Visit Supplier Webpage Request for quotation
CAS: 1392275-56-7
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: GS-7340 Hemifumarate Visit Supplier Webpage Request for quotation
CAS: 1392275-56-7
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: Tenofovir Alafenamide Hemifumarate Visit Supplier Webpage Request for quotation
CAS: 1392275-56-7
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Yuanye Bio-Technology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: GS-7340 (hemifumarate) Visit Supplier Webpage Request for quotation
CAS: 1392275-56-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
SHANDONG SIHUAN PHARMACEUTICAL CO., LTD
Product Name: Tenofovir Alafenamide fumarate Request for quotation
CAS: 1392275-56-7
Tel: 0531-88990216
Email: fairouz@sdsihuanpharm.com
Mobile: 13335127975
QQ: 824027327 Click to send a QQ messageSend QQ message
View History
替诺福韦艾拉酚胺富马酸半盐
ETHYL 2-[(4-METHYLPHENYL)SULFONYL]ACETATE
酪氨酸激酶抑制剂(TYROSINE KINASE INHIBITOR)
Imazalil sulphate (ISO)
(2-溴代乙基)环己烷
2-吗啉-4-基乙酸乙酯
2-AMINO-3-(2-FLUORO-4-METHYLPHENYL)PROPANOIC ACID HYDROCHLORIDE
2-(硫杂环丁烷-3-亚基)乙酸甲酯
双(二苄叉丙酮)钯
达拉菲尼中间体2
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