桑皮酮H(桑黄酮H)

Name	kuwanon H
Synonyms	Alvanin G Albanin G kuwanon H NSC 356889 kuwanone H Moracenin A 8-[(1S,5R,6S)-6-[2,4-dihydroxy-3-(3-methylbut-2-enyl)benzoyl]-5-(2,4-dihydroxyphenyl)-3-methyl-1-cyclohex-2-enyl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methylbut-2-enyl)chromen-4-one 8-[(1S)-6α-[2,4-Dihydroxy-3-(3-methyl-2-butenyl)benzoyl]-5β-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1β-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
CAS	76472-87-2

biological activity	Kuwanon H is a flavonoid in cortex Mori, a non-peptide bombesin receptor antagonist. Kuwanon H can specifically inhibit the binding of intracellular hormone-releasing peptide CRP to the (GRP-preferring receptor) receptor with a Ki value of 290 nM.
Target	Ki: 290 nM (GRP-preferring recepotr)

Last Update：2024-04-09 20:45:29

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桑皮酮H(桑黄酮H)

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