美海屈林萘二磺酸盐
mebhydroline 1,5-naphthalenedisulfonate
CAS: 6153-33-9
Molecular Formula: C48H48N4O6S2
美海屈林萘二磺酸盐 - Names and Identifiers
| Name | mebhydroline 1,5-naphthalenedisulfonate |
| Synonyms | incidal DIAZOLINE mebhydrolin napadisilate Mebhydrolin napadisylate MEBHYDROLIN NAPADISYLATE Mebhydroline napadisylate MEBHYDROLINE NAPADISYLATE MEBHYDROLINE 1,5-NAPHTHALENEDISULFONATE mebhydroline 1,5-naphthalenedisulfonate MEBHYDROLINE 1,5-NAPHTHALENEDISULFONATE SALT 9-Benzyl-N-Methyl-1,2,3,4-Tetrahydro-A-Carboline |
| CAS | 6153-33-9 |
| EINECS | 228-170-3 |
| InChI | InChI=1/2C19H20N2.C10H8O6S2/c2*1-20-12-11-19-17(14-20)16-9-5-6-10-18(16)21(19)13-15-7-3-2-4-8-15;11-17(12,13)9-5-1-3-7-8(9)4-2-6-10(7)18(14,15)16/h2*2-10H,11-14H2,1H3;1-6H,(H,11,12,13)(H,14,15,16) |
美海屈林萘二磺酸盐 - Physico-chemical Properties
| Molecular Formula | C48H48N4O6S2 |
| Molar Mass | 841.05 |
| Density | 0.9799 (rough estimate) |
| Melting Point | 280°C (rough estimate) |
| Boling Point | 409.28°C (rough estimate) |
| Flash Point | 230.4°C |
| Solubility | DMSO (Slightly, Heated), Methanol (Slightly, Heated) |
| Vapor Presure | 1.51E-08mmHg at 25°C |
| Appearance | neat |
| Color | White to Off-White |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.8676 (estimate) |
| Use | Used as a pharmaceutical Intermediate |
| In vitro study | Mebhydrolin is a specific histamine H 1 -receptor antagonist with minimal sedative properties and comparing it with the effects of chlorpromazine, the archetypical phenothiazine. Mebhydrolin exerts an antihistaminic effect over the period of the ethanol interaction study. |
美海屈林萘二磺酸盐 - Risk and Safety
| WGK Germany | 3 |
| RTECS | QJ6845000 |
美海屈林萘二磺酸盐 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.378 ml | 11.89 ml | 23.78 ml |
| 5 mM | 0.476 ml | 2.378 ml | 4.756 ml |
| 10 mM | 0.238 ml | 1.189 ml | 2.378 ml |
| 5 mM | 0.048 ml | 0.238 ml | 0.476 ml |
Last Update：2024-01-02 23:10:35
美海屈林萘二磺酸盐 - Reference Information
| biological activity | Mebhydrolin Napadisylate (Diazoline, Diazolin, Incidal, Omeril) is an antihistamine, for the treatment of allergies. |
| Target | Histamine H1-receptor |
| Use | for pharmaceutical intermediates |
Last Update：2024-04-10 22:41:03
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