贝美前列素杂质5 - Names and Identifiers
Name | 17- Phenyl Trinor Prostaglandin F2α Methyl Amide
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Synonyms | Bimatoprost Impurity 5 Bimatoprost Impurity E Bimatoprost Methyl Amide 17- Phenyl Trinor Prostaglandin F2α Methyl Amide 17-phenyl trinor Prostaglandin F2.alpha. methyl amide (~{Z})-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-methylhept-5-enamide 5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-methyl-, (5Z)-
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CAS | 155206-01-2
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贝美前列素杂质5 - Physico-chemical Properties
Molecular Formula | C24H35NO4
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Molar Mass | 401.54 |
Density | 1.159±0.06 g/cm3(Predicted) |
Boling Point | 621.5±55.0 °C(Predicted) |
Solubility | DMSO (Slightly), Ethanol |
Appearance | Clear Colourless Solution |
pKa | 14.25±0.20(Predicted) |
Storage Condition | -20°C Freezer |
贝美前列素杂质5 - Introduction
17-Phenyl Trinor Prostaglandin F2α Methyl Amide, also known as 17-Phenyl Trinor Prostaglandin F2α Methyl Amide, is a synthetic prostaglandin analog. Its chemical structure is similar to the natural prostaglandin F2α.
17- Phenyl Trinor Prostaglandin F2α Methyl Amide is a white crystalline solid, colorless, soluble in organic solvents such as ethanol, methanol and dimethyl sulfoxide. Its molecular formula is C24H35NO3 and its relative molecular mass is 393.53.
17- Phenyl Trinor Prostaglandin F2α Methyl Amide is commonly used in the medical field as an anti-inflammatory and anti-platelet aggregation agent. It has the effect of contraction of uterine smooth muscle, can be used for the treatment of menstrual disorders, dysmenorrhea and uterine bleeding and other gynecological diseases. In addition, it is also used to control increased intraocular pressure caused by eye diseases such as glaucoma.
The preparation method of 17- Phenyl Trinor Prostaglandin F2α Methyl Amide is mainly obtained by chemical synthesis. One method of synthesis is the reaction of the precursor compound bimatoprost acid (17-Phenyl Trinor Prostaglandin F2α) with methylamine to yield the 17-Phenyl Trinor Prostaglandin F2α Methyl Amide.
When using 17- Phenyl Trinor Prostaglandin F2α Methyl Amide, the following safety information should be noted: It is a strong irritant and may cause damage to the skin, eyes and respiratory tract. Therefore, when handling or touching 17- Phenyl Trinor Prostaglandin F2α Methyl Amide, appropriate protective measures such as safety glasses, gloves and protective clothing must be worn. At the same time, it also needs to be stored in a closed container, away from fire and oxidizing agents.
In addition, for individuals allergic to 17- Phenyl Trinor Prostaglandin F2α Methyl Amide, exposure to it may cause allergic reactions. Therefore, proper allergy testing is required before use.
This is an introduction to the properties, uses, methods and safety information of 17- Phenyl Trinor Prostaglandin F2α Methyl Amide. For further information, please consult a professional or refer to the relevant literature.
Last Update:2024-04-09 21:11:58