顺式-1-N-叔丁氧羰基-4-羟基-D-脯氨酸甲酯

顺式-1-N-叔丁氧羰基-4-羟基-D-脯氨酸甲酯 - Names and Identifiers

Name	N-tert-Butoxycarbonyl-cis-4-hydroxy-D-proline methyl ester
Synonyms	Boc-Cis-D-Hyp-OMe Methyl cis-Boc-4-hydroxy-D-prolinate Methy cis-1-Boc-4-hydroxy-D-prolinate METHYL CIS-1-BOC-4-HYDROXY-D-PROLINATE Boc-cis-4-hydroxy-D-proline methyl ester N-tert-Butoxycarbonyl-cis-4-hydroxy-D-proline methyl ester (2R,4R)-1-tert-butyl 2-Methyl 4-hydroxypyrrolidine-1,2-dicarboxy (2R,4R)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate (2R,4R)-1-tert-butyl 2-Methyl 4-hydro×ypyrrolidine-1,2-dicarbo×ylate 1-tert-butyl 2-methyl (2R,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate (2R,4R)-4-Hydroxy-1,2-pyrrolidinedicarboxylicacid 1-(1,1-dimethylethyl) 2-methyl ester 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2R,4R)-
CAS	114676-69-6
EINECS	675-952-9
InChI	InChI=1/C11H19NO5/c1-11(2,3)17-10(15)12-6-7(13)5-8(12)9(14)16-4/h7-8,13H,5-6H2,1-4H3/t7-,8-/m1/s1

顺式-1-N-叔丁氧羰基-4-羟基-D-脯氨酸甲酯 - Physico-chemical Properties

Molecular Formula	C11H19NO5
Molar Mass	245.27
Density	1.216±0.06 g/cm3(Predicted)
Melting Point	76 °C
Boling Point	335.2±42.0 °C(Predicted)
Flash Point	156.6°C
Vapor Presure	8.47E-06mmHg at 25°C
Appearance	Powder
Color	White
pKa	14.27±0.40(Predicted)
Storage Condition	Sealed in dry,Store in freezer, under -20°C
Refractive Index	1.5
MDL	MFCD00797548

顺式-1-N-叔丁氧羰基-4-羟基-D-脯氨酸甲酯 - Introduction

Cis-1-BOC-4-hydroxy-D-proline methyl ester is an organic compound with the following properties:

1. appearance: usually white or white crystalline powder.

2. Solubility: Soluble in common organic solvents such as methanol, ethanol and dimethylformamide.

3. stability: relatively stable at room temperature, but heat, light and acidic conditions may cause decomposition reaction.

The main uses of cis-1-BOC-4-hydroxy-D-proline methyl ester are as follows:

1. chemical synthesis: can be used as an intermediate in organic synthesis, for the synthesis of other compounds, such as drugs, dyes, etc.

2. Peptide synthesis: It can be used as an important raw material for the synthesis of peptides or proteins of specific sequences.

preparation method: there are many preparation methods of cis-1-BOC-4-hydroxy-D-proline methyl ester. a common synthesis method is to react 4-hydroxy-D-proline with a methyl esterification agent (such as methanol and methyl carbonic acid), and carry out esterification reaction under alkaline conditions to obtain the target product.

Safety Information: Methyl cis-1-BOC-4-hydroxy-D-proline is dangerous and may cause irritation to the skin, eyes and respiratory tract. During the operation, you should wear appropriate protective equipment to avoid direct contact with skin, eyes or inhalation of dust. At the same time, pay attention to the safe operation during storage and handling, and ensure that it is far away from the fire source and oxidant. If necessary, it is necessary to follow the relevant safety operation procedures or consult a professional.

Last Update：2024-04-09 21:11:58