Thalidomide-4-O-C2-NH2 MedChemExpress (MCE)

Product Name	Thalidomide 4'-ether-alkylC2-amine hydrochloride
Synonyms	189432 halidomide-linker 6 -ether-alkylC2-amine Thalidomide-linker 6 Thalidomide-O-C2-NH2 hydrochloride Thalidomide-linker 6 hydrochloride Thalidomide 4'-ether-alkylC2-amine Synonyms 189432 halidomide-linker 6 -ether-alkylC2-amine Thalidomide-linker 6 Thalidomide-O-C2-NH2 hydrochloride Thalidomide-linker 6 hydrochloride Thalidomide 4'-ether-alkylC2-amine Thalidomide 4'-ether-alkylC2-amine hydrochloride Thalidomide 4'-ether-alkylC2-amine (hydrochloride) 4-(2-aminoethoxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride
CAS	2341840-99-9
EINECS
Chemical Formula	C15H16ClN3O5
Molecular Weight	353.76
inchi
Package	5 mg;10 mg;25 mg;50 mg
Price	Email to quote
Descriptions	Thalidomide-4-O-C2-NH2 hydrochloride Thalidomide-4-O-C2-NH2 hydrochloride MedChemExpress (MCE) HY-136162 2341840-99-9 99.37% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months Descriptions Thalidomide-4-O-C2-NH2 hydrochloride Thalidomide-4-O-C2-NH2 hydrochloride MedChemExpress (MCE) HY-136162 2341840-99-9 99.37% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. Thalidomide-4-O-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. PROTACs contain two different ligands connected by a linker one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. Cereblon \| \| \| \| \| \| \| \| \| \| [1]. Turk BE, et al. Binding of thalidomide to alpha1-acid glycoprotein may be involved in its inhibition of tumor necrosis factor alpha production. Proc Natl Acad Sci U S A. 1996 93(15):7552‐7556. [Content Brief]
Last Update	2025-04-01 14:45:47

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